The emergence of cyclic peptides: The potential of bioengineered peptide drugs

P Thapa, MJ Espiritu, C Cabalteja… - International Journal of …, 2014 - Springer
Studies into N-to C-terminal cyclic peptide backbone structures have provided for the lateral
transition of important principles and strategies that clearly resonate within the world of …

Kalium 3.0 is a comprehensive depository of natural, artificial, and labeled polypeptides acting on potassium channels

NA Krylov, VM Tabakmakher, DA Yureva… - Protein …, 2023 - Wiley Online Library
Here, we introduce the third release of Kalium database (http://kaliumdb. org/), a manually
curated comprehensive depository that accumulates data on polypeptide ligands of …

[HTML][HTML] Electrophysiological Characterization of Ts6 and Ts7, K+ Channel Toxins Isolated through an Improved Tityus serrulatus Venom Purification Procedure

FA Cerni, MB Pucca, S Peigneur, CM Cremonez… - Toxins, 2014 - mdpi.com
In Brazil, Tityus serrulatus (Ts) is the species responsible for most of the scorpion related
accidents. Among the Ts toxins, the neurotoxins with action on potassium channels (α-KTx) …

[HTML][HTML] Identification and Venom Characterization of Two Scorpions from the State of Chihuahua Mexico: Chihuahuanus coahuliae and Chihuahuanus crassimannus

C Alvarado-Gonzalez, H Clement… - Toxins, 2023 - mdpi.com
Chihuahua is the largest state in Mexico. The ecosystem of this region is composed of large
area of bushes, forests, and grasslands, which allows for a specific diversity of fauna; among …

Centipede envenomation: Clinical importance and the underlying molecular mechanisms

R Ombati, L Luo, S Yang, R Lai - Toxicon, 2018 - Elsevier
Centipede bites are usually characterized by mildly to moderately painful encounters with
humans, however, they are relatively infrequent. The vast majority of centipede …

[HTML][HTML] Amazonian scorpions and scorpionism: integrating toxinological, clinical, and phylogenetic data to combat a human health crisis in the world's most diverse …

A Borges, MR Graham, DM Cândido… - Journal of Venomous …, 2021 - SciELO Brasil
Venom from Amazonian scorpions of the genus Tityus contains components capable of
eliciting a distinct clinical, mostly neurological, syndrome. This contrasts with the mainly …

Labelled animal toxins as selective molecular markers of ion channels: Applications in neurobiology and beyond

AI Kuzmenkov, AA Vassilevski - Neuroscience Letters, 2018 - Elsevier
Animal toxins are traditional and indispensible molecular tools that find application in
different fields of biochemistry, neurobiology and pharmacology. These compounds possess …

Зоотоксинология: биоэкологические и биомедицинские аспекты

ДБ Гелашвили, ВН Крылов, ЕБ Романова - 2015 - elibrary.ru
В учебном пособии на основе анализа мировой научной литературы приведены
современные данные о важнейших ядовитых представителях фауны Земли, а также …

[HTML][HTML] BmK AEP, an anti-epileptic peptide distinctly affects the gating of brain subtypes of voltage-gated sodium channels

F Zhang, Y Wu, X Zou, Q Tang, F Zhao… - International Journal of …, 2019 - mdpi.com
BmK AEP, a scorpion peptide purified form the venom of Buthus martensii Karsch, has been
reported to display anti-epileptic activity. Voltage-gated sodium channels (VGSCs) are …

Evolution of alternative methodologies of scorpion antivenoms production

AO Carmo, M Chatzaki, CCR Horta, BF Magalhães… - Toxicon, 2015 - Elsevier
Scorpionism represents a serious public health problem resulting in the death of children
and debilitated individuals. Scorpion sting treatment employs various strategies including …