[HTML][HTML] Inhalable nanoparticle-based dry powder formulations for respiratory diseases: challenges and strategies for translational research
The emergence of novel respiratory infections (eg, COVID-19) and expeditious development
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …
An evolving perspective on novel modified release drug delivery systems for inhalational therapy
Introduction Drugs delivered via the lungs are predominantly used to treat various
respiratory disorders, including asthma, chronic obstructive pulmonary diseases, respiratory …
respiratory disorders, including asthma, chronic obstructive pulmonary diseases, respiratory …
[HTML][HTML] Inhaled curcumin mesoporous polydopamine nanoparticles against radiation pneumonitis
T Chen, B Zhuang, Y Huang, Y Liu, B Yuan… - … Pharmaceutica Sinica B, 2022 - Elsevier
Radiation therapy is an effective method to kill cancer cells and shrink tumors using high-
energy X-ray or γ-ray. Radiation pneumonitis (RP) is one of the most serious complications …
energy X-ray or γ-ray. Radiation pneumonitis (RP) is one of the most serious complications …
[HTML][HTML] Scalable production and in vitro efficacy of inhaled erlotinib nanoemulsion for enhanced efficacy in non-small cell lung cancer (NSCLC)
Non-small cell lung cancer (NSCLC) is a global concern as one of the leading causes of
cancer deaths. The treatment options for NSCLC are limited to systemic chemotherapy …
cancer deaths. The treatment options for NSCLC are limited to systemic chemotherapy …
Interactions between CuO NPs and PS: The release of copper ions and oxidative damage
Y Cao, S Tian, Y Geng, L Zhang, Q Zhao, J Chen… - Science of The Total …, 2023 - Elsevier
Abstract Copper oxide nanoparticles (CuO NPs) can adversely affect lung health possibly by
inducing oxidative damage through the release of copper ions. However, the migration and …
inducing oxidative damage through the release of copper ions. However, the migration and …
Evaluating the impact of hydrophobic silicon dioxide in the interfacial properties of lung surfactant films
The interaction of hydrophobic silicon dioxide particles (fumed silicon dioxide), as model air
pollutants, and Langmuir monolayers of a porcine lung surfactant extract has been studied …
pollutants, and Langmuir monolayers of a porcine lung surfactant extract has been studied …
In Silico Modeling Approaches Coupled with In Vitro Characterization in Predicting In Vivo Performance of Drug Delivery System Formulations
A Kambayashi - Molecular pharmaceutics, 2023 - ACS Publications
Optimization of the in vivo performance of dosage forms in humans is essential in
developing not only conventional formulations but also drug delivery system (DDS) …
developing not only conventional formulations but also drug delivery system (DDS) …
In vitro-in vivo correlation of cascade impactor data for orally inhaled pharmaceutical aerosols
In vitro-in vivo correlation is the establishment of a predictive relationship between in vitro
and in vivo data. In the context of cascade impactor results of orally inhaled pharmaceutical …
and in vivo data. In the context of cascade impactor results of orally inhaled pharmaceutical …
[HTML][HTML] Fluid Films as Models for Understanding the Impact of Inhaled Particles in Lung Surfactant Layers
E Guzmán - Coatings, 2022 - mdpi.com
Pollution is currently a public health problem associated with different cardiovascular and
respiratory diseases. These are commonly originated as a result of the pollutant transport to …
respiratory diseases. These are commonly originated as a result of the pollutant transport to …
Elucidation of the effect of added fines on the performance of dry powder inhalation formulations
M Stankovic-Brandl, S Radivojev, P Sailer… - International Journal of …, 2022 - Elsevier
Dry powder inhalers (DPIs) are regularly used to treat respiratory diseases. Adding extrinsic
fine excipient particles to the blend of active pharmaceutical ingredient (API) and carrier is …
fine excipient particles to the blend of active pharmaceutical ingredient (API) and carrier is …