Mitochondrial oxidative stress in the tumor microenvironment and cancer immunoescape: foe or friend?

CL Kuo, A Ponneri Babuharisankar, YC Lin… - Journal of biomedical …, 2022 - Springer
The major concept of" oxidative stress" is an excess elevated level of reactive oxygen
species (ROS) which are generated from vigorous metabolism and consumption of oxygen …

Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress‐and aging‐related diseases

AG Panossian, T Efferth, AN Shikov… - Medicinal research …, 2021 - Wiley Online Library
Adaptogens comprise a category of herbal medicinal and nutritional products promoting
adaptability, resilience, and survival of living organisms in stress. The aim of this review was …

PM2. 5 exposure and asthma development: the key role of oxidative stress

K Liu, S Hua, L Song - Oxidative Medicine and Cellular …, 2022 - Wiley Online Library
Oxidative stress is defined as the imbalance between reactive oxygen species (ROS)
production and the endogenous antioxidant defense system, leading to cellular damage …

Chemical Biology of H2S Signaling through Persulfidation

MR Filipovic, J Zivanovic, B Alvarez… - Chemical …, 2018 - ACS Publications
Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …

[HTML][HTML] The role of oxidative stress in neurodegenerative diseases

GH Kim, JE Kim, SJ Rhie, S Yoon - Experimental neurobiology, 2015 - ncbi.nlm.nih.gov
Oxidative stress is induced by an imbalanced redox states, involving either excessive
generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. The …

Hyperglycemia and oxidative stress: An integral, updated and critical overview of their metabolic interconnections

P González, P Lozano, G Ros, F Solano - International Journal of …, 2023 - mdpi.com
This review focuses on the multiple and reciprocal relationships that exist between oxidative
stress, hyperglycemia and diabetes and related metabolic disorders. Human metabolism …

Melatonin: an ancient molecule that makes oxygen metabolically tolerable

LC Manchester, A Coto‐Montes, JA Boga… - Journal of pineal …, 2015 - Wiley Online Library
Melatonin is remarkably functionally diverse with actions as a free radical scavenger and
antioxidant, circadian rhythm regulator, anti‐inflammatory and immunoregulating molecule …

Targeting oxidative stress as a therapeutic approach for idiopathic pulmonary fibrosis

C Estornut, J Milara, MA Bayarri, N Belhadj… - Frontiers in …, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease characterized by an
abnormal reepithelialisation, an excessive tissue remodelling and a progressive fibrosis …

Oxidative stress and cancer: an overview

V Sosa, T Moliné, R Somoza, R Paciucci… - Ageing research …, 2013 - Elsevier
Reactive species, which mainly include reactive oxygen species (ROS), are products
generated as a consequence of metabolic reactions in the mitochondria of eukaryotic cells …

Oxidative stress in obstructive sleep apnea and intermittent hypoxia–revisited–the bad ugly and good: implications to the heart and brain

L Lavie - Sleep medicine reviews, 2015 - Elsevier
Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), is linked with
increased reactive oxygen species/reactive nitrogen species (ROS/RNS) and oxidative …