Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G Jin… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Supramolecular polymers in aqueous media

E Krieg, MMC Bastings, P Besenius… - Chemical …, 2016 - ACS Publications
This review discusses one-dimensional supramolecular polymers that form in aqueous
media. First, naturally occurring supramolecular polymers are described, in particular …

Protein assembly: versatile approaches to construct highly ordered nanostructures

Q Luo, C Hou, Y Bai, R Wang, J Liu - Chemical Reviews, 2016 - ACS Publications
Nature endows life with a wide variety of sophisticated, synergistic, and highly functional
protein assemblies. Following Nature's inspiration to assemble protein building blocks into …

[HTML][HTML] Cell-penetrating peptides: Design strategies beyond primary structure and amphipathicity

D Kalafatovic, E Giralt - molecules, 2017 - mdpi.com
Efficient intracellular drug delivery and target specificity are often hampered by the presence
of biological barriers. Thus, compounds that efficiently cross cell membranes are the key to …

“Click” reactions: a versatile toolbox for the synthesis of peptide-conjugates

W Tang, ML Becker - Chemical Society Reviews, 2014 - pubs.rsc.org
Peptides that comprise the functional subunits of proteins have been conjugated to versatile
materials (biomolecules, polymers, surfaces and nanoparticles) in an effort to modulate cell …

Noncanonical amino acids for hypoxia-responsive peptide self-assembly and fluorescence

B Hu, N Song, Y Cao, M Li, X Liu, Z Zhou… - Journal of the …, 2021 - ACS Publications
Design of endogenous stimuli-responsive amino acids allows for precisely modulating
proteins or peptides under a biological microenvironment and thereby regulating their …

Self-assembling peptide-based building blocks in medical applications

H Acar, S Srivastava, EJ Chung… - Advanced drug delivery …, 2017 - Elsevier
Peptides and peptide-conjugates, comprising natural and synthetic building blocks, are an
increasingly popular class of biomaterials. Self-assembled nanostructures based on …

Bioengineered protein-based nanocage for drug delivery

EJ Lee, NK Lee, IS Kim - Advanced drug delivery reviews, 2016 - Elsevier
Nature, in its wonders, presents and assembles the most intricate and delicate protein
structures and this remarkable phenomenon occurs in all kingdom and phyla of life. Of these …

Gradated assembly of multiple proteins into supramolecular nanomaterials

GA Hudalla, T Sun, JZ Gasiorowski, H Han, YF Tian… - Nature materials, 2014 - nature.com
Biomaterials exhibiting precise ratios of different bioactive protein components are critical for
applications ranging from vaccines to regenerative medicine, but their design is often …

Fabrication and mechanical properties of engineered protein‐based adhesives and fibers

J Sun, J Su, C Ma, R Göstl, A Herrmann… - Advanced …, 2020 - Wiley Online Library
Protein‐based structural biomaterials are of great interest for various applications because
the sequence flexibility within the proteins may result in their improved mechanical and …