Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
Supramolecular polymers in aqueous media
This review discusses one-dimensional supramolecular polymers that form in aqueous
media. First, naturally occurring supramolecular polymers are described, in particular …
media. First, naturally occurring supramolecular polymers are described, in particular …
Protein assembly: versatile approaches to construct highly ordered nanostructures
Nature endows life with a wide variety of sophisticated, synergistic, and highly functional
protein assemblies. Following Nature's inspiration to assemble protein building blocks into …
protein assemblies. Following Nature's inspiration to assemble protein building blocks into …
[HTML][HTML] Cell-penetrating peptides: Design strategies beyond primary structure and amphipathicity
D Kalafatovic, E Giralt - molecules, 2017 - mdpi.com
Efficient intracellular drug delivery and target specificity are often hampered by the presence
of biological barriers. Thus, compounds that efficiently cross cell membranes are the key to …
of biological barriers. Thus, compounds that efficiently cross cell membranes are the key to …
“Click” reactions: a versatile toolbox for the synthesis of peptide-conjugates
W Tang, ML Becker - Chemical Society Reviews, 2014 - pubs.rsc.org
Peptides that comprise the functional subunits of proteins have been conjugated to versatile
materials (biomolecules, polymers, surfaces and nanoparticles) in an effort to modulate cell …
materials (biomolecules, polymers, surfaces and nanoparticles) in an effort to modulate cell …
Noncanonical amino acids for hypoxia-responsive peptide self-assembly and fluorescence
B Hu, N Song, Y Cao, M Li, X Liu, Z Zhou… - Journal of the …, 2021 - ACS Publications
Design of endogenous stimuli-responsive amino acids allows for precisely modulating
proteins or peptides under a biological microenvironment and thereby regulating their …
proteins or peptides under a biological microenvironment and thereby regulating their …
Self-assembling peptide-based building blocks in medical applications
Peptides and peptide-conjugates, comprising natural and synthetic building blocks, are an
increasingly popular class of biomaterials. Self-assembled nanostructures based on …
increasingly popular class of biomaterials. Self-assembled nanostructures based on …
Bioengineered protein-based nanocage for drug delivery
Nature, in its wonders, presents and assembles the most intricate and delicate protein
structures and this remarkable phenomenon occurs in all kingdom and phyla of life. Of these …
structures and this remarkable phenomenon occurs in all kingdom and phyla of life. Of these …
Gradated assembly of multiple proteins into supramolecular nanomaterials
Biomaterials exhibiting precise ratios of different bioactive protein components are critical for
applications ranging from vaccines to regenerative medicine, but their design is often …
applications ranging from vaccines to regenerative medicine, but their design is often …
Fabrication and mechanical properties of engineered protein‐based adhesives and fibers
Protein‐based structural biomaterials are of great interest for various applications because
the sequence flexibility within the proteins may result in their improved mechanical and …
the sequence flexibility within the proteins may result in their improved mechanical and …