The maintenance of a healthy and functional mitochondrial network is critical during
development as well as throughout life in the response to physiological adaptations and …

Anemia of Inflammation Anemia of inflammation is a common normocytic, normochromic
anemia associated with systemic inflammation that increases the level of hepcidin and …

INTRODUCTION A reference atlas of human cell types is a major goal for the field. Here, we
set out to generate single-cell atlases of both gene expression (this study) and chromatin …

Autophagy and the ubiquitin–proteasome system (UPS) are the two major intracellular
quality control and recycling mechanisms that are responsible for cellular homeostasis in …

High blood glucose level (hyperglycemia) is a leading indicator of diabetes mellitus (DM).
Erythrocytes are the most abundant cells in the circulation and the first to perceive changes …

Human red blood cells (RBC) are highly differentiated cells that have lost all organelles and
most intracellular machineries during their maturation process. RBC are fundamental for the …

Hematopoietic stem and progenitor cells (HSPCs) maintain the adult blood system, and their
dysregulation causes a multitude of diseases. However, the differentiation journeys toward …

We recently developed fluorescence-activated cell sorting (FACS)-based methods to purify
morphologically and functionally discrete populations of cells, each representing specific …

SARS-CoV-2 infection is associated with lower blood oxygen levels, even in patients without
hypoxia requiring hospitalization. This discordance illustrates the need for a more unifying …

Phagocytosis, a critical early event in the microbicidal response of neutrophils, is now
appreciated to serve multiple functions in a variety of cell types. Professional phagocytes …