Triplex forming ability of oligonucleotides containing 2′-O-methyl-2-thiouridine or 2-thiothymidine

I Okamoto, K Seio, M Sekine - Bioorganic & medicinal chemistry letters, 2006 - Elsevier
The triplex forming ability of oligonucleotides containing 2′-O-methyl-2-thiouridine (s2Um)
and 2-thiothymidine (s2T) was studied. The UV melting experiments revealed that triplex …

Base pairing of anhydrohexitol nucleosides with 2, 6-diaminopurine, 5-methylcytosine and uracil as base moiety

V Boudou, L Kerremans, B De Bouvere… - Nucleic acids …, 1999 - academic.oup.com
Hexitol nucleic acids (HNAs) with modified bases (5-methylcytosine, 2, 6-diaminopurine or
uracil) were synthesized. The introduction of the 5-methylcytosine base demonstrates that N …

Synthesis and properties of oligodeoxynucleotides containing 5-carboxy-2′-deoxycytidines

M Sumino, A Ohkubo, H Taguchi, K Seio… - Bioorganic & medicinal …, 2008 - Elsevier
5-Carboxy-2′-deoxycytidine [Formula: see text] was synthesized as an anion-carrier to
seek a new possibility of modified oligodeoxynucleotides capable of stabilization of …

Probing ambiguous base‐pairs by genetic transformation with XNA templates

V Pezo, G Schepers, C Lambertucci, P Marlière… - …, 2014 - Wiley Online Library
The templating potential of anhydrohexitol oligonucleotides bearing ambiguous bases was
studied in vivo, by using a selection screen for mosaic heteroduplex plasmids in Escherichia …

In Situ Visualizing Nascent RNA by Exploring DNA-Templated Oxidative Amination of 4-Thiouridine

J Shang, L He, J Wang, A Tong… - Bioconjugate Chemistry, 2021 - ACS Publications
Tracking and mapping the nascent RNA molecules in cells is essential for deciphering
embryonic development and neuronal differentiation. Here, we utilized 4-thiouridine (s4U) …

Chemical synthesis of the nucleoside antibiotic capuramycin

G Xiao, H He - European Journal of Organic Chemistry, 2021 - Wiley Online Library
Capuramycin is an important lead nucleoside antibiotic for the development of new
therapeutic agents against the multidrug‐resistant Mycobacterium tuberculosis infections …

Selective recognition of CG interruption by 2′, 4′-BNA having 1-isoquinolone as a nucleobase in a pyrimidine motif triplex formation

Y Hari, S Obika, M Sekiguchi, T Imanishi - Tetrahedron, 2003 - Elsevier
To develop a novel nucleoside analogue for the effective recognition of CG interruption in a
homopurine–homopyrimidine tract of double-stranded DNA (dsDNA), we succeeded in the …

Modulation of the stereoselectivity and reactivity of glycosylation via (p-Tol) 2SO/Tf2O preactivation strategy: From O-, C-sialylation to general O-, N-glycosylation

GJ Liu, CY Li, XT Zhang, W Du, ZY Gu… - Chinese Chemical …, 2018 - Elsevier
The synthesis of O-, C-, and N-glycoconjugates has continuously been an attractive
research subject due to the growing biological importance of various glycoconjugates. In …

Sulfonamide bearing oligonucleotides: Simple synthesis and efficient RNA recognition

P Kumar, N Chandak, P Nielsen, PK Sharma - Bioorganic & medicinal …, 2012 - Elsevier
Four pyrimidine nucleosides wherein a benzensulfonamide group is linked to the C-5
position of the uracil nucleobase through a triazolyl or an alkynyl linker were prepared by Cu …

3′-Amino-2′, 4′-BNA: novel bridged nucleic acids having an N3′→ P5′ phosphoramidate linkage

S Obika, M Onoda, K Morita, J Andoh… - Chemical …, 2001 - pubs.rsc.org
3′-Amino-2′,4′-BNA: novel bridged nucleic acids having an N3′→P5′ phosphoramidate
linkage - Chemical Communications (RSC Publishing) DOI:10.1039/B105640A Royal Society of …