Obesity management in adults: a review

A Elmaleh-Sachs, JL Schwartz, CT Bramante… - Jama, 2023 - jamanetwork.com
Importance Obesity affects approximately 42% of US adults and is associated with increased
rates of type 2 diabetes, hypertension, cardiovascular disease, sleep disorders …

[HTML][HTML] Excess body weight: Novel insights into its roles in obesity comorbidities

X Zhang, S Ha, HCH Lau, J Yu - Seminars in cancer biology, 2023 - Elsevier
Excess body weight is a global health problem due to sedentary lifestyle and unhealthy diet,
affecting 2 billion population worldwide. Obesity is a major risk factor for metabolic diseases …

Tirzepatide once weekly for the treatment of obesity

AM Jastreboff, LJ Aronne, NN Ahmad… - … England Journal of …, 2022 - Mass Medical Soc
Background Obesity is a chronic disease that results in substantial global morbidity and
mortality. The efficacy and safety of tirzepatide, a novel glucose-dependent insulinotropic …

Effect of subcutaneous semaglutide vs placebo as an adjunct to intensive behavioral therapy on body weight in adults with overweight or obesity: the STEP 3 …

TA Wadden, TS Bailey, LK Billings, M Davies, JP Frias… - Jama, 2021 - jamanetwork.com
Importance Weight loss improves cardiometabolic risk factors in people with overweight or
obesity. Intensive lifestyle intervention and pharmacotherapy are the most effective …

Clinical practice guidelines for the perioperative nutrition, metabolic, and nonsurgical support of patients undergoing bariatric procedures–2019 update: cosponsored …

JI Mechanick, C Apovian, S Brethauer… - Surgery for Obesity and …, 2020 - Elsevier
Objective The development of these updated clinical practice guidelines (CPG) was
commissioned by the American Association of Clinical Endocrinologists, The Obesity …

Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 2· 4 mg for weight …

LB Enebo, KK Berthelsen, M Kankam, MT Lund… - The Lancet, 2021 - thelancet.com
Background Cagrilintide, a long-acting amylin analogue, and semaglutide 2· 4 mg, a
glucagon-like peptide-1 analogue, are both being investigated as options for weight …

Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active …

JP Frias, MA Nauck, J Van, ME Kutner, X Cui… - The Lancet, 2018 - thelancet.com
Background LY3298176 is a novel dual glucose-dependent insulinotropic polypeptide (GIP)
and glucagon-like peptide-1 (GLP-1) receptor agonist that is being developed for the …

Changing the global obesity narrative to recognize and reduce weight stigma: a position statement from the World Obesity Federation

S Nutter, LA Eggerichs, TS Nagpal… - Obesity …, 2024 - Wiley Online Library
Weight stigma, defined as pervasive misconceptions and stereotypes associated with higher
body weight, is both a social determinant of health and a human rights issue. It is imperative …

Effects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in obese adults: A pilot study

K Gabel, KK Hoddy, N Haggerty, J Song… - … and healthy aging, 2018 - content.iospress.com
BACKGROUND: Time restricted feeding decreases energy intake without calorie counting
and may be a viable option for weight loss. However, the effect of this diet on body weight in …

AGA clinical practice guideline on pharmacological interventions for adults with obesity

E Grunvald, R Shah, R Hernaez, AK Chandar… - Gastroenterology, 2022 - Elsevier
Background & Aims Pharmacological management of obesity improves outcomes and
decreases the risk of obesity-related complications. This American Gastroenterological …