[HTML][HTML] Type 2 Diabetes Prevention Programs—From Proof-of-Concept Trials to National Intervention and Beyond
J Tuomilehto, M Uusitupa, EW Gregg… - Journal of clinical …, 2023 - mdpi.com
The prevention of type 2 diabetes (T2D) in high-risk people with lifestyle interventions has
been demonstrated by several randomized controlled trials. The intervention effect has …
been demonstrated by several randomized controlled trials. The intervention effect has …
[HTML][HTML] The mechanisms of glycolipid metabolism disorder on vascular injury in type 2 diabetes
X Chen, C Shi, Y Wang, H Yu, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Patients with diabetes have severe vascular complications, such as diabetic nephropathy,
diabetic retinopathy, cardiovascular disease, and neuropathy. Devastating vascular …
diabetic retinopathy, cardiovascular disease, and neuropathy. Devastating vascular …
[HTML][HTML] Effect of high glucose supplementation on pulmonary fibrosis involving reactive oxygen species and TGF-β
W Ning, X Xu, S Zhou, X Wu, H Wu, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
This study explored the profibrotic impact of high glucose in the lung and potential
mechanisms using latent TGF-β-induced human epithelial cell pulmonary fibrosis and …
mechanisms using latent TGF-β-induced human epithelial cell pulmonary fibrosis and …
[HTML][HTML] Lifestyle Intervention Guided by Group and Internet-Based Counseling in the T2D-GENE Trial Supports Its Applicability and Feasibility
U Schwab, M Lankinen, M Uusitupa, M Laakso - Nutrients, 2023 - mdpi.com
Type 2 diabetes (T2D) can be prevented or postponed by lifestyle modifications as shown by
previous intervention studies. In most of these studies, participants have received resource …
previous intervention studies. In most of these studies, participants have received resource …
High glucose intake exacerbates experimental autoimmune prostatitis through mitochondrial reactive oxygen species-dependent TGF-β activation-mediated Th17 …
D Niu, SY Yue, X Wang, WY Li, L Zhang, HX Du… - International …, 2024 - Elsevier
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common inflammatory
immune disease of the urogenital system. High glucose intake is considered to be a …
immune disease of the urogenital system. High glucose intake is considered to be a …
Tyrosine nitration of glucagon impairs its function: Extending the role of heme in T2D pathogenesis
X Yin, G Ni, X Zhang, S Fu, H Li, Z Gao - Journal of Inorganic Biochemistry, 2024 - Elsevier
New studies raise the possibility that the higher glucagon (GCG) level present in type 2
diabetes (T2D) is a compensatory mechanism to enhance β-cell function, rather than induce …
diabetes (T2D) is a compensatory mechanism to enhance β-cell function, rather than induce …
Tyrosine Nitration of Glucagon Impairs Glucose Homeostasis by Attenuating the Intraislet Glucagon Signaling: Extending the Role of Heme in T2d
X Ying, G Ni, X Zhang, Z Gao, S Fu, H Li… - Available at SSRN … - papers.ssrn.com
Abstract Glucagon (GCG), a 29 amino acid peptide produced by the a cells in the pancreas,
has received the most attention because of important roles in glucose metabolism. The new …
has received the most attention because of important roles in glucose metabolism. The new …