Synthesizing the evidence for ketamine and esketamine in treatment-resistant depression: an international expert opinion on the available evidence and …

RS McIntyre, JD Rosenblat… - American Journal of …, 2021 - Am Psychiatric Assoc
Replicated international studies have underscored the human and societal costs associated
with major depressive disorder. Despite the proven efficacy of monoamine-based …

The abuse liability of ketamine: a scoping review of preclinical and clinical studies

TT Le, IP Cordero, MY Jawad, J Swainson… - Journal of psychiatric …, 2022 - Elsevier
While ketamine has been used clinically over the past decades, it has only been recently
shown to be a promising therapy for treatment-resistant depression (TRD). However …

Ketamine for the acute treatment of severe suicidal ideation: double blind, randomised placebo controlled trial

M Abbar, C Demattei, W El-Hage, PM Llorca, L Samalin… - bmj, 2022 - bmj.com
Objective To confirm the rapid onset anti-suicidal benefits of ketamine in the short term and
at six weeks, overall and according to diagnostic group. Design Prospective, double blind …

Ketamine and esketamine in suicidal thoughts and behaviors: a systematic review

F Jollant, R Colle, TML Nguyen… - Therapeutic …, 2023 - journals.sagepub.com
Background: More than 2% of the general population experience suicidal ideas each year
and a large number of them will attempt suicide. Evidence-based therapeutic options to …

Efficacy and safety of racemic ketamine and esketamine for depression: a systematic review and meta-analysis

A Bahji, CA Zarate, GH Vazquez - Expert opinion on drug safety, 2022 - Taylor & Francis
Background Racemic ketamine and esketamine have demonstrated rapid antidepressant
effects. We aimed to review the efficacy and safety of racemic and esketamine for …

Prevention and management of common adverse effects of ketamine and esketamine in patients with mood disorders

F Ceban, JD Rosenblat, K Kratiuk, Y Lee… - CNS drugs, 2021 - Springer
The emerging roles of ketamine and esketamine as effective rapid-acting antidepressants
hold promise for patients suffering from treatment-resistant depression and/or major …

The therapeutic role of ketamine and esketamine in treating psychopathological domains of depression

MY Jawad, JD Di Vincenzo, S Badulescu, KM Teopiz… - …, 2023 - Elsevier
Over the past two decades, ketamine has emerged as a novel effective and rapid-acting
antidepressant. While the vast majority of studies on ketamine have focused on its ability to …

Efficacy of ketamine and esketamine on functional outcomes in treatment-resistant depression: a systematic review

J Ng, JD Rosenblat, LMW Lui, KM Teopiz, Y Lee… - Journal of affective …, 2021 - Elsevier
Background In recent years, ketamine and esketamine treatment have demonstrated rapid
antidepressant effects in adults with treatment-resistant depression (TRD). Hitherto …

Ketamine as a novel psychopharmacotherapy for eating disorders: Evidence and future directions

A Ragnhildstveit, M Slayton, LK Jackson, M Brendle… - Brain Sciences, 2022 - mdpi.com
Eating disorders (EDs) are serious, life-threatening psychiatric conditions associated with
physical and psychosocial impairment, as well as high morbidity and mortality. Given the …

Canadian Network for Mood and Anxiety Treatments (CANMAT) 2023 Update on Clinical Guidelines for Management of Major Depressive Disorder in Adults: Réseau …

RW Lam, SH Kennedy, C Adams… - The Canadian …, 2024 - journals.sagepub.com
Résumé Contexte Le Réseau canadien pour les traitements de l'humeur et de l'anxiété
(CANMAT) a publié les dernières lignes directrices cliniques pour le traitement du trouble …