The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection

A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
The coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome
coronavirus 2 presents with a spectrum of clinical manifestations from asymptomatic or mild …

Sepsis: a review of advances in management

J Rello, F Valenzuela-Sánchez, M Ruiz-Rodriguez… - Advances in …, 2017 - Springer
Infections represent a common health problem in people of all ages. Usually, the response
given to them is appropriate and so little treatment is needed. Sometimes, however, the …

[PDF][PDF] Sepsis and septic shock: Guideline-based management

S Dugar, C Choudhary, A Duggal - Cleve Clin J Med, 2020 - christopherreeve.org
Sepsis is a life-threatening organ dysfunction that results from the body's response to
infection. It requires prompt recognition, appropriate antibiotics, careful hemodynamic …

Mechanisms of decompensation and organ failure in cirrhosis: from peripheral arterial vasodilation to systemic inflammation hypothesis

M Bernardi, R Moreau, P Angeli, B Schnabl… - Journal of hepatology, 2015 - Elsevier
The peripheral arterial vasodilation hypothesis has been most influential in the field of
cirrhosis and its complications. It has given rise to hundreds of pathophysiological studies in …

Early prediction of sepsis in the ICU using machine learning: a systematic review

M Moor, B Rieck, M Horn, CR Jutzeler… - Frontiers in …, 2021 - frontiersin.org
Background: Sepsis is among the leading causes of death in intensive care units (ICUs)
worldwide and its recognition, particularly in the early stages of the disease, remains a …

COVID-19 and Sepsis

ZK Tufan, B Kayaaslan, M Mer - Turkish journal of medical …, 2021 - journals.tubitak.gov.tr
The COVID-19 pandemic has created a major alteration in the medical literature including
the sepsis discussion. From the outset of the pandemic, various reports have indicated that …

[HTML][HTML] Molecularly imprinted polymer based electrochemical biosensors: Overcoming the challenges of detecting vital biomarkers and speeding up diagnosis

RD Crapnell, NC Dempsey-Hibbert, M Peeters… - Talanta Open, 2020 - Elsevier
Electrochemical biosensors for the detection of vital biomarkers is a well-established
technology that utilises a transducer and recognition element in tandem to determine the …

Serum ferritin levels in inflammation: a retrospective comparative analysis between COVID-19 and emergency surgical non-COVID-19 patients

F Banchini, GM Cattaneo, P Capelli - World Journal of Emergency Surgery, 2021 - Springer
Background SARS-CoV-2 infection has spread worldwide, and the pathogenic mechanism
is still under investigation. The presence of a huge inflammatory response, defined as …

Dynamic immune/inflammation precision medicine: the good and the bad inflammation in infection and cancer

JF Rossi, ZY Lu, C Massart, K Levon - Frontiers in immunology, 2021 - frontiersin.org
Normal or “good” inflammation process starts from a local cellular response against injury or
any infectious agent, with the activation of neutrophils, macrophages, Langerhans cells …

Phagocytosis, degranulation and extracellular traps release by neutrophils—the current knowledge, pharmacological modulation and future prospects

B Gierlikowska, A Stachura, W Gierlikowski… - Frontiers in …, 2021 - frontiersin.org
Neutrophils are crucial elements of innate immune system, which assure host defense via a
range of effector functions, such as phagocytosis, degranulation, and NET formation. The …