Glucocorticoids (corticosterone in birds and rodents and cortisol in all other mammals) are
glucoregulatory hormones that are synthesized in response to a range of stimuli including …

The adrenal cortices produce a variety of steroid hormones (corticosteroids), including
mineralocorticoids (eg, aldosterone), glucocorticoids (eg, cortisol), and adrenal androgens …

BACKGROUND & AIMS: Adrenal insufficiency (AI) is reported in critically ill patients with
cirrhosis and is associated with increased mortality. It is unclear if AI is an underlying …

BACKGROUND & AIMS: Adrenal insufficiency (AI) has been reported in patients with
advanced liver disease. Diagnosing AI is problematic owing to controversies in using total …

Abstract Background/Aims: The diagnostic criteria for critical illness-related corticoid
insufficiency (CIRCI) are not well established, particularly for children. In addition to …

Published data on adrenocortical function in septic shock have enrolled patients at various
stages of critical illness and predominantly used plasma total cortisol, with minimal …

Background Traumatic brain injury (TBI) is commonly associated with disturbances of the
hypothalamic–pituitary–adrenal axis secretion. Cerebral microdialysis techniques have …

A central feature of the endocrine pathophysiology of septic shock is thought to be the
existence of adrenal dysfunction. Based on changes in glucocorticoid secretion and …

The stress system receives and integrates diverse cognitive, emotional, neurosensory, and
peripheral somatic signals that arrive through distinct pathways. Activation of the stress …

Adequate adrenocortical function is essential for survival in critical illness. Most critically ill
patients display elevated plasma cortisol concentrations, which reflects activation of the …