Introducing new vaccines in low-and middle-income countries: challenges and approaches

A Guignard, N Praet, V Jusot, M Bakker… - Expert review of …, 2019 - Taylor & Francis
Introduction: The number of new vaccine introductions (NVIs) in low and middle-income
countries (LMICs) has markedly increased since 2010, raising challenges to often …

[HTML][HTML] High residual carriage of vaccine-serotype Streptococcus pneumoniae after introduction of pneumococcal conjugate vaccine in Malawi

TD Swarthout, C Fronterre, J Lourenço… - Nature …, 2020 - nature.com
There are concerns that pneumococcal conjugate vaccines (PCVs) in sub-Saharan Africa
sub-optimally interrupt Streptococcus pneumoniae vaccine-serotype (VT) carriage and …

Population impact and effectiveness of monovalent rotavirus vaccination in urban Malawian children 3 years after vaccine introduction: ecological and case-control …

N Bar-Zeev, KC Jere, A Bennett… - Clinical infectious …, 2016 - academic.oup.com
Background. Rotavirus vaccines have been introduced in many low-income African
countries including Malawi in 2012. Despite early evidence of vaccine impact, determining …

[HTML][HTML] Impact and effectiveness of 13-valent pneumococcal conjugate vaccine on population incidence of vaccine and non-vaccine serotype invasive pneumococcal …

N Bar-Zeev, TD Swarthout, DB Everett… - The Lancet Global …, 2021 - thelancet.com
Background The population impact of pneumococcal conjugate vaccines (PCVs) depends
on direct and indirect protection. Following Malawi's introduction of the 13-valent PCV …

[HTML][HTML] Predictive value of pulse oximetry for mortality in infants and children presenting to primary care with clinical pneumonia in rural Malawi: a data linkage study

T Colbourn, C King, J Beard, T Phiri, M Mdala… - PLoS …, 2020 - journals.plos.org
Background The mortality impact of pulse oximetry use during infant and childhood
pneumonia management at the primary healthcare level in low-income countries is …

[HTML][HTML] Methodological challenges in measuring vaccine effectiveness using population cohorts in low resource settings

C King, J Beard, AC Crampin, A Costello… - Vaccine, 2015 - Elsevier
Post-licensure real world evaluation of vaccine implementation is important for establishing
evidence of vaccine effectiveness (VE) and programme impact, including indirect effects …

[HTML][HTML] Impact of monovalent rotavirus vaccine on diarrhoea-associated post-neonatal infant mortality in rural communities in Malawi: a population-based birth cohort …

N Bar-Zeev, C King, T Phiri, J Beard, H Mvula… - The Lancet Global …, 2018 - thelancet.com
Background Rotavirus is a major contributor to child mortality. The effect of rotavirus vaccine
on diarrhoea mortality has been estimated in middle-income but not low-income settings …

[HTML][HTML] Predictors of uptake and timeliness of newly introduced pneumococcal and rotavirus vaccines, and of measles vaccine in rural Malawi: a population cohort …

H Mvula, E Heinsbroek, M Chihana, AC Crampin… - Plos one, 2016 - journals.plos.org
Background Malawi introduced pneumococcal conjugate vaccine (PCV13) and monovalent
rotavirus vaccine (RV1) in 2011 and 2012 respectively, and is planning the introduction of a …

[HTML][HTML] Re-evaluating the cost and cost-effectiveness of rotavirus vaccination in Bangladesh, Ghana, and Malawi: A comparison of three rotavirus vaccines

C Pecenka, F Debellut, N Bar-Zeev, P Anwari… - Vaccine, 2018 - Elsevier
Introduction Diarrhea is a leading cause of mortality worldwide and rotavirus accounts for
many of these deaths. As of August 2018, 96 countries have introduced rotavirus vaccines …

[HTML][HTML] Population genetic structure, antibiotic resistance, capsule switching and evolution of invasive pneumococci before conjugate vaccination in Malawi

C Chaguza, JE Cornick, CP Andam, RA Gladstone… - Vaccine, 2017 - Elsevier
Introduction Pneumococcal infections cause a high death toll in Sub Saharan Africa (SSA)
but the recently rolled out pneumococcal conjugate vaccines (PCV) will reduce the disease …