Repair and regeneration of large bone defects is still a challenge, especially for defects
which are the irregular and complex. Three-dimension (3D) printing, as an advanced …

Dripping, jetting and tip streaming have been studied up to a certain point separately by both
fluid mechanics and microfluidics communities, the former focusing on fundamental aspects …

Biofabrication of living structures with desired topology and functionality requires the
interdisciplinary effort of practitioners of the physical, life and engineering sciences. Such …

Cancer is intrinsically complex, comprising both heterogeneous cellular compositions and
microenvironmental cues. During the various stages of cancer initiation, development, and …

Vascularization is one of the great challenges that tissue engineering faces in order to
achieve sizeable tissue and organ substitutes that contain living cells. There are instances …

Bottom-up tissue engineering technologies address two of the main limitations of top-down
tissue engineering approaches: the control of mass transfer and the fabrication of a …

We present a method to create multi-layered engineered tissue composites consisting of
human skin fibroblasts and keratinocytes which mimic skin layers. Three-dimensional (3D) …

Tissue engineering is emerging as a potential therapeutic approach to overcome limitations
of cell therapy, like cell retention and survival, as well as to mechanically support the …

Fabrication of nerve conduits for perfectly repairing or replacing damaged peripheral nerve
is an urgent demand worldwide, but it is also a formidable clinical challenge. In the last …

Bioprinting is a method by which a cell-encapsulating bioink is patterned to create complex
tissue architectures. Given the potential impact of this technology on neural research, we …