Faecalibacterium: a bacterial genus with promising human health applications

R Martín, D Rios-Covian, E Huillet… - FEMS Microbiology …, 2023 - academic.oup.com
In humans, many diseases are associated with alterations in gut microbiota, namely
increases or decreases in the abundance of specific bacterial groups. One example is the …

Assembling symbiotic bacterial species into live therapeutic consortia that reconstitute microbiome functions

RA Oliveira, EG Pamer - Cell Host & Microbe, 2023 - cell.com
Increasing experimental evidence suggests that administering live commensal bacterial
species can optimize microbiome composition and lead to reduced disease severity and …

Infant microbiome cultivation and metagenomic analysis reveal Bifidobacterium 2'-fucosyllactose utilization can be facilitated by coexisting species

YC Lou, BE Rubin, MC Schoelmerich… - Nature …, 2023 - nature.com
The early-life gut microbiome development has long-term health impacts and can be
influenced by factors such as infant diet. Human milk oligosaccharides (HMOs), an essential …

A Keystone Gut Bacterium Christensenella minuta—A Potential Biotherapeutic Agent for Obesity and Associated Metabolic Diseases

WS Ang, JWF Law, V Letchumanan, KW Hong… - Foods, 2023 - mdpi.com
A new next-generation probiotic, Christensenella minuta was first discovered in 2012 from
healthy human stool and described under the phylum Firmicutes. C. minuta is a …

Nutritional and host environments determine community ecology and keystone species in a synthetic gut bacterial community

AS Weiss, LS Niedermeier, A von Strempel… - Nature …, 2023 - nature.com
A challenging task to understand health and disease-related microbiome signatures is to
move beyond descriptive community-level profiling towards disentangling microbial …

Identifying keystone species in microbial communities using deep learning

XW Wang, Z Sun, H Jia, S Michel-Mata… - Nature Ecology & …, 2024 - nature.com
Previous studies suggested that microbial communities can harbour keystone species
whose removal can cause a dramatic shift in microbiome structure and functioning. Yet, an …

Gut commensals and their metabolites in health and disease

HK Krishnamurthy, M Pereira, J Bosco… - Frontiers in …, 2023 - frontiersin.org
Purpose of review This review comprehensively discusses the role of the gut microbiome
and its metabolites in health and disease and sheds light on the importance of a holistic …

Role-playing between environmental pollutants and human gut microbiota: A complex bidirectional interaction

F Giambò, C Costa, M Teodoro, C Fenga - Frontiers in Medicine, 2022 - frontiersin.org
There is a growing interest in the characterization of the involvement of toxicant and
pollutant exposures in the development and the progression of several diseases such as …

How does quorum sensing of intestinal bacteria affect our health and mental status?

LMT Dicks - Microorganisms, 2022 - mdpi.com
The human gut is host to almost 3000 microbial species, of which 90% are bacteria. Quorum
sensing (QS) molecules generated by intestinal bacteria are important in establishing …

Rapid evolution of a novel protective symbiont into keystone taxon in Caenorhabditis elegans microbiota

A Wu-Chuang, KA Bates, D Obregon… - Scientific Reports, 2022 - nature.com
Protective microbes have a major role in shaping host–pathogen interactions, but their
relative importance in the structure of the host microbiota remains unclear. Here, we used a …