Neuroinflammation and the kynurenine pathway in CNS disease: molecular mechanisms and therapeutic implications
Diseases of the central nervous system (CNS) remain a significant health, social and
economic problem around the globe. The development of therapeutic strategies for CNS …
economic problem around the globe. The development of therapeutic strategies for CNS …
GluN2B subunit selective N-methyl-D-aspartate receptor ligands: Democratizing recent progress to assist the development of novel neurotherapeutics
V Ugale, R Deshmukh, D Lokwani… - Molecular Diversity, 2023 - Springer
N-methyl-D-aspartate receptors (NMDARs) play essential roles in vital aspects of brain
functions. NMDARs mediate clinical features of neurological diseases and thus, represent a …
functions. NMDARs mediate clinical features of neurological diseases and thus, represent a …
Antiaging Strategies and Remedies: A Landscape of Research Progress and Promise
Aging is typified by a gradual loss of physiological fitness and accumulation of cellular
damage, leading to deteriorated functions and enhanced vulnerability to diseases. Antiaging …
damage, leading to deteriorated functions and enhanced vulnerability to diseases. Antiaging …
Synthesis, docking, 3-D-Qsar, and biological assays of novel indole derivatives targeting serotonin transporter, dopamine D2 receptor, and Mao-A enzyme: In the …
C Cerda-Cavieres, G Quiroz, P Iturriaga-Vásquez… - Molecules, 2020 - mdpi.com
A series of 27 compounds of general structure 2, 3-dihydro-benzo [1, 4] oxazin-4-yl)-2-{4-[3-
(1 H-3indolyl)-propyl]-1-piperazinyl}-ethanamides, Series I: 7 (a–o) and (2-{4-[3-(1 H-3 …
(1 H-3indolyl)-propyl]-1-piperazinyl}-ethanamides, Series I: 7 (a–o) and (2-{4-[3-(1 H-3 …
The Role of Oxidative Kynurenine Metabolism in Mediating Hippocampal Cognitive Deficits in a Mouse Model of Chronic Inflammation
MNH Mithaiwala - 2022 - search.proquest.com
Cognitive impairments represent a growing and costly public health concern; in the US
alone, 1 out of every nine individuals suffer from cognitive dysfunction. Age, genetic …
alone, 1 out of every nine individuals suffer from cognitive dysfunction. Age, genetic …
[PDF][PDF] Modelling depression-related behaviours in mice
M Viktorov - 2022 - research-information.bris.ac.uk
Major depressive disorder (MDD) is a globally prevalent, complex disorder with a wide
range of symptoms. Current-line antidepressants are only effective in minority of patients …
range of symptoms. Current-line antidepressants are only effective in minority of patients …
C-reactive protein in patients with major depressive disorder in Zagazig university hospitals.
A Ashraf, A El-Latif, R Reda… - Zagazig University …, 2021 - zumj.journals.ekb.eg
Background: The relationship between inflammation and psychiatric disorders has been
widely debated. Psychiatric patients had features of inflammation, such as high levels of …
widely debated. Psychiatric patients had features of inflammation, such as high levels of …
[PDF][PDF] A Case Report of Posterior Reversible Encephalopathy Syndrome in a Libyan Child Stung by Scorpion and Review of the Literatures
S Alougly, S Elbragathy, A Alhsony, A Elarwah… - pdfs.semanticscholar.org
Posterior reversible encephalopathy syndrome (PRESS) is a disorder of reversible
subcortical vasogenic brain edema predominantly involving the parieto-occipital regions of …
subcortical vasogenic brain edema predominantly involving the parieto-occipital regions of …
[PDF][PDF] C-reactive protein in patients with major depressive disorder in Zagazig university hospitals.
RR Abd El-Latif, AES Mohamed, AS Ibrahim… - academia.edu
Background: The relationship between inflammation and psychiatric disorders has been
widely debated. Psychiatric patients had features of inflammation, such as high levels of …
widely debated. Psychiatric patients had features of inflammation, such as high levels of …
[PDF][PDF] Zagazig University Medical Journa l
A Ashraf, RR Abd El-Latif, A El-Shabrawy, AS Ibrahim - 2021 - digitalcommons.aaru.edu.jo
Background: The relationship between inflammation and psychiatric disorders has been
widely debated. Psychiatric patients had features of inflammation, such as high levels of …
widely debated. Psychiatric patients had features of inflammation, such as high levels of …