[HTML][HTML] Recent advances in heat shock proteins in cancer diagnosis, prognosis, metabolism and treatment

S Yang, H Xiao, L Cao - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Heat shock proteins (HSPs) are a group of proteins, also known as molecular chaperones,
which participate in protein folding and maturation in response to stresses or high …

Chinese herbal medicine for primary liver cancer therapy: perspectives and challenges

K Li, K Xiao, S Zhu, Y Wang, W Wang - Frontiers in Pharmacology, 2022 - frontiersin.org
Primary liver cancer (PLC) is one of the most common solid malignancies. However, PLC
drug development has been slow, and first-line treatments are still needed; thus, studies …

Cancer metabolism control by natural products: Pyruvate kinase M2 targeting therapeutics

AH El‐Far, SK Al Jaouni, X Li, J Fu - Phytotherapy Research, 2022 - Wiley Online Library
Glycolysis is the primary source of energy for cancer growth and metastasis. The shift in
metabolism from mitochondrial oxidative phosphorylation to aerobic glycolysis is called the …

Emerging role of terpenoids for the treatment of cancer: A review

B Chopra, AK Dhingra, KL Dhar… - Mini Reviews in …, 2021 - ingentaconnect.com
Aim: Terpenes are natural compounds found in several organisms belonging to the animal
and plant kingdom, therefore, constitute the largest class of natural products and were a rich …

Protective mechanism of Astragalus Polysaccharides against Cantharidin‐induced liver injury determined in vivo by liquid chromatography/mass spectrometry …

X Huang, W Tang, C Lin, Z Sa, M Xu… - Basic & Clinical …, 2021 - Wiley Online Library
Cantharidin (CTD) is a promising anticancer drug; however, its dosage is limited by
hepatotoxicity. We previously showed that Astragalus polysaccharides (APS) effectively …

[Retracted] Cantharidin Inhibits Proliferation of Liver Cancer by Inducing DNA Damage via KDM4A‐Dependent Histone H3K36 Demethylation

C Wei, X Deng, S Gao, X Wan… - … and Alternative Medicine, 2022 - Wiley Online Library
Objective. To investigate the effect of cantharidin on DNA damage in hepatocellular
carcinoma cells and its possible mechanism. Methods. Cell proliferation assay and terminal …

The evidence framework of traditional Chinese medicine injection (Aidi injection) in controlling malignant pleural effusion: A clustered systematic review and meta …

CQ Wang, J Xu, H Jiang, XT Zheng, Y Zhang… - Phytomedicine, 2023 - Elsevier
Abstract Introduction Aidi injection (Aidi), a traditional Chinese medicine injection, is often
practiced to control malignant pleural effusion (MPE). Objectives We performed a registered …

Unraveling the role of male reproductive tract and haemolymph in cantharidin-exuding Lydus trimaculatus and Mylabris variabilis (Coleoptera: Meloidae): a …

E Fratini, M Salvemini, F Lombardo, M Muzzi, M Molfini… - BMC genomics, 2021 - Springer
Background Meloidae (blister beetles) are known to synthetize cantharidin (CA), a toxic and
defensive terpene mainly stored in male accessory glands (MAG) and emitted outward …

Development of glycyrrhetinic acid and folate modified cantharidin loaded solid lipid nanoparticles for targeting hepatocellular carcinoma

Y Xu, M Wang, S Ning, Z Yang, L Zhou, X Xia - Molecules, 2022 - mdpi.com
Cantharidin (CTD) is the major component of anticancer drugs obtained from Mylabris
Cichorii and has a good inhibitory effect on several cancers, including hepatocellular …

Diels–Alder Cycloadditions of Bio-Derived Furans with Maleimides as a Sustainable «Click» Approach towards Molecular, Macromolecular and Hybrid Systems

KI Galkin, IV Sandulenko, AV Polezhaev - Processes, 2021 - mdpi.com
This mini-review highlights the recent research trends in designing organic or organic-
inorganic hybrid molecular, biomolecular and macromolecular systems employing …