This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

Objective: The authors provide an evidenced-based summary of the literature on the clinical
application of psychedelic drugs in psychiatric disorders. Methods: Searches of PubMed and …

Classic psychedelics produce altered states of consciousness that individuals often interpret
as meaningful experiences. Across a number of human studies, when the participant-rated …

Psychiatric disorders are highly prevalent, often devastating diseases that negatively impact
the lives of millions of people worldwide. Although their etiological and diagnostic …

Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

How do experiences in nature or in spiritual contemplation or in being moved by music or
with psychedelics promote mental and physical health? Our proposal in this article is awe …

Background Terminally ill patients may experience existential distress, depression, or
anxiety, limiting quality of life in the final stage. Existing psychotherapeutic or …

Investigating changes in brain function induced by mind-altering substances such as LSD is
a powerful method for interrogating and understanding how mind interfaces with brain, by …

Rationale Major depressive disorder is one of the leading global causes of disability, for
which the classic serotonergic psychedelics have recently reemerged as a potential …

Psychedelic-assisted therapy may represent an upcoming paradigm shift in the treatment of
mental health problems as recent clinical trials have demonstrated strong evidence of their …