Clinical biology of the pituitary adenoma

S Melmed, UB Kaiser, MB Lopes, J Bertherat… - Endocrine …, 2022 - academic.oup.com
All endocrine glands are susceptible to neoplastic growth, yet the health consequences of
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …

The epidemiology of pituitary adenomas

AF Daly, A Beckers - Endocrinol Metab Clin North Am, 2020 - books.google.com
Prolactinomas and nonfunctioning pituitary adenomas are the most frequent subtypes of
clinically relevant adenomas, followed by acromegaly and Cushing's disease. The incidence …

Novel insights into pituitary tumorigenesis: genetic and epigenetic mechanisms

V Srirangam Nadhamuni, M Korbonits - Endocrine reviews, 2020 - academic.oup.com
Substantial advances have been made recently in the pathobiology of pituitary tumors.
Similar to many other endocrine tumors, over the last few years we have recognized the role …

The natural history and treatment of non-functioning pituitary adenomas (non-functioning PitNETs)

MP Yavropoulou, M Tsoli, K Barkas… - Endocrine-Related …, 2020 - erc.bioscientifica.com
Non-functioning pituitary adenomas, recently alternatively termed pituitary neuroendocrine
tumours (NFpitNETs), are mostly benign neoplasms that are not associated with a hormonal …

Chromosomal instability in the prediction of pituitary neuroendocrine tumors prognosis

H Lasolle, MH Elsensohn, A Wierinckx, E Alix… - Acta neuropathologica …, 2020 - Springer
The purpose of this study was to analyze the impact of copy number variations (CNV) on
sporadic pituitary neuroendocrine tumors (PitNETs) prognosis, to identify specific prognosis …

A proposed clinical classification for pituitary neoplasms to guide therapy and prognosis

KKY Ho, M Fleseriu, J Wass, L Katznelson… - The Lancet Diabetes & …, 2024 - thelancet.com
No comprehensive classification system that guides prognosis and therapy of pituitary
adenomas exists. The 2022 WHO histopathology-based classification system can only be …

Update on the genetics of pituitary tumors

S Barry, M Korbonits - Endocrinology and Metabolism Clinics, 2020 - endo.theclinics.com
The prevalence of symptomatic pituitary neuroendocrine tumors (PitNETs) is approximately
1 in 1000 in the general population. Most of these tumors occur sporadically and are not part …

Clinical and genetic characteristics in patients under 30 years with sporadic pituitary adenomas

I Martínez de LaPiscina, N Portillo Najera… - European Journal of …, 2021 - academic.oup.com
Objective Pituitary adenomas (PA) are rare in young patients, and additional studies are
needed to fully understand their pathogenesis in this population. We describe the clinical …

Germline loss-of-function PAM variants are enriched in subjects with pituitary hypersecretion

G Trivellin, AF Daly, LC Hernández-Ramírez… - Frontiers in …, 2023 - frontiersin.org
Introduction Pituitary adenomas (PAs) are common, usually benign tumors of the anterior
pituitary gland which, for the most part, have no known genetic cause. PAs are associated …

Large scale molecular studies of pituitary neuroendocrine tumors: Novel markers, mechanisms and translational perspectives

R Peculis, H Niedra, V Rovite - Cancers, 2021 - mdpi.com
Simple Summary Pituitary neuroendocrine tumors are non-cancerous tumors of the pituitary
gland, that may overproduce hormones leading to serious health conditions or due to tumor …