Periodontitis involves the loss of connective tissue attachment and alveolar bone. Single cell
RNA-seq experiments have provided new insight into how resident cells and infiltrating …

The purpose of this review was to evaluate data generated by animal models of
intervertebral disc (IVD) degeneration published in the last decade and show how this has …

Host genetic polymorphisms are recognized as a critical determinant of diversity in clinical
symptoms of Coronavirus disease 2019 (COVID-19). Accordingly, this study aimed to …

Chondroitin sulfate (CS) is the most abundant and widely distributed glycosaminoglycan
(GAG) in the human body. As a component of proteoglycans (PGs) it has numerous roles in …

The soft‐hard tissue interface of the human periodontium is responsible for periodontal
homeostasis and is essential for normal oral activities. This soft‐hard tissue interface is …

Emerging evidence suggests that nerves within the tumor microenvironment play a crucial
role in regulating angiogenesis. Neurotransmitters and neuropeptides released by nerves …

Background. The extracellular matrix of the PNS/CNS is unusual in that it is dominated by
glycosaminoglycans, especially hyaluronan, whose space filling and hydrating properties …

Rheumatoid arthritis (RA) is one of the most common autoimmune diseases. Inflammation of
the synovial fluid propagates the pathological process of angiogenesis. Semaphorins play a …

Angiogenesis, as a process occurring under the regulation of a variety of factors, is one of
the important ways of vascular development. It coexists in a variety of pathological and …

Background Semaphorins have been found to play important roles in multiple malignancy-
related processes. However, the role of Semaphorin 4B (SEMA4B) in lung cancer remains …