Inherited cardiac arrhythmias
PJ Schwartz, MJ Ackerman, C Antzelevitch… - Nature reviews Disease …, 2020 - nature.com
The main inherited cardiac arrhythmias are long QT syndrome, short QT syndrome,
catecholaminergic polymorphic ventricular tachycardia and Brugada syndrome. These rare …
catecholaminergic polymorphic ventricular tachycardia and Brugada syndrome. These rare …
2017 AHA/ACC/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College …
SM Al-Khatib, WG Stevenson, MJ Ackerman… - Journal of the American …, 2018 - jacc.org
The recommendations listed in this clinical practice guideline are, whenever possible,
evidence-based. An initial extensive evidence review, which included literature derived from …
evidence-based. An initial extensive evidence review, which included literature derived from …
The Lancet Commission to reduce the global burden of sudden cardiac death: a call for multidisciplinary action
E Marijon, K Narayanan, K Smith, S Barra, C Basso… - The Lancet, 2023 - thelancet.com
Despite major advancements in cardiovascular medicine, sudden cardiac death (SCD)
continues to be an enormous medical and societal challenge, claiming millions of lives …
continues to be an enormous medical and societal challenge, claiming millions of lives …
Role of the autonomic nervous system in modulating cardiac arrhythmias
MJ Shen, DP Zipes - Circulation research, 2014 - Am Heart Assoc
The autonomic nervous system plays an important role in the modulation of cardiac
electrophysiology and arrhythmogenesis. Decades of research has contributed to a better …
electrophysiology and arrhythmogenesis. Decades of research has contributed to a better …
Channelopathies that lead to sudden cardiac death: clinical and genetic aspects
JR Skinner, A Winbo, D Abrams, J Vohra… - Heart, Lung and …, 2019 - Elsevier
Forty per cent (40%) of sudden unexpected natural deaths in people under 35 years of age
are associated with a negative autopsy, and the cardiac ion channelopathies are the prime …
are associated with a negative autopsy, and the cardiac ion channelopathies are the prime …
Molecular and tissue mechanisms of catecholaminergic polymorphic ventricular tachycardia
MJ Wleklinski, PJ Kannankeril… - The Journal of …, 2020 - Wiley Online Library
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a stress‐induced cardiac
channelopathy that has a high mortality in untreated patients. Our understanding has grown …
channelopathy that has a high mortality in untreated patients. Our understanding has grown …
Catecholaminergic polymorphic ventricular tachycardia in children: analysis of therapeutic strategies and outcomes from an international multicenter registry
TM Roston, JM Vinocur, KR Maginot… - Circulation …, 2015 - Am Heart Assoc
Background—Catecholaminergic polymorphic ventricular tachycardia is an uncommon,
potentially lethal, ion channelopathy. Standard therapies have high failure rates and little is …
potentially lethal, ion channelopathy. Standard therapies have high failure rates and little is …
RYR2 channel inhibition is the principal mechanism of flecainide action in CPVT
DO Kryshtal, DJ Blackwell, CL Egly, AN Smith… - Circulation …, 2021 - Am Heart Assoc
Rationale: The class Ic antiarrhythmic drug flecainide prevents ventricular tachyarrhythmia in
patients with catecholaminergic polymorphic ventricular tachycardia (CPVT), a disease …
patients with catecholaminergic polymorphic ventricular tachycardia (CPVT), a disease …
Efficacy of flecainide in the treatment of catecholaminergic polymorphic ventricular tachycardia: a randomized clinical trial
Importance Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a potentially
lethal genetic arrhythmia syndrome characterized by polymorphic ventricular tachycardia …
lethal genetic arrhythmia syndrome characterized by polymorphic ventricular tachycardia …
Recommendations for participation in leisure-time physical activity and competitive sports of patients with arrhythmias and potentially arrhythmogenic conditions. Part …
H Heidbuchel, E Arbelo, F D'Ascenzi… - EP …, 2021 - academic.oup.com
This paper belongs to a series of recommendation documents for participation in leisure-
time physical activity and competitive sports by the European Association of Preventive …
time physical activity and competitive sports by the European Association of Preventive …