From LncRNA to metastasis: The MALAT1-EMT axis in cancer progression

R Thapa, O Afzal, M Afzal, G Gupta, AA Bhat… - … -Research and Practice, 2023 - Elsevier
Cancer is a complex disease that causes abnormal genetic changes and unchecked cellular
growth. It also causes a disruption in the normal regulatory processes that leads to the …

Exploring the anti‐cancer potential of dietary phytochemicals for the patients with breast cancer: a comprehensive review

M Sohel, S Aktar, P Biswas, MA Amin… - Cancer …, 2023 - Wiley Online Library
Background The most common and deadly cancer in female is breast cancer (BC) and new
incidence and deaths related to this cancer are rising. Aims Several issues, that is, high cost …

Oncoinformatic screening of the gene clusters involved in the HER2-positive breast cancer formation along with the in silico pharmacodynamic profiling of selective …

AKMH Morshed, S Al Azad, MAR Mia, MF Uddin… - Molecular …, 2023 - Springer
The HER2-positive patients occupy~ 30% of the total breast cancer patients globally where
no prevalent drugs are available to mitigate the frequent metastasis clinically except …

Study of MDM2 as Prognostic Biomarker in Brain-LGG Cancer and Bioactive Phytochemicals Inhibit the p53-MDM2 Pathway: A Computational Drug Development …

P Biswas, S Bibi, Q Yousafi, A Mehmood, S Saleem… - Molecules, 2023 - mdpi.com
An evaluation of the expression and predictive significance of the MDM2 gene in brain lower-
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …

Target-specificity of different amyrin subunits in impeding HCV influx mechanism inside the human cells considering the quantum tunnel profiles and molecular strings …

A Jabin, MF Uddin, S Al Azad, A Rahman… - In Silico …, 2023 - Springer
HCV is a hepatotropic RNA virus recognized for its frequent virulence and fatality worldwide.
Despite many vaccine development programs underway, researchers are on a quest for …

Metal oxide nanocarrier for targeted drug delivery towards the treatment of global infectious diseases: A review

S Saha, MR Ali, MA Khaleque, MS Bacchu… - Journal of Drug Delivery …, 2023 - Elsevier
Conventional systems for drug delivery vehicles face many limitations, thus, there have been
an extensive investigation for alternative strategies. In the last decade, nanotechnology had …

Comprehensive exploration of Biochanin A as an oncotherapeutics potential in the treatment of multivarious cancers with molecular insights

M Sohel - Phytotherapy Research, 2024 - Wiley Online Library
Cancer is considered a leading cause of mortality. This rising cancer death rate and several
existing limitations like side effects, poor efficacies, and high cost of the present …

Molecular Dynamics Simulation and Pharmacoinformatic Integrated Analysis of Bioactive Phytochemicals from Azadirachta indica (Neem) to Treat Diabetes Mellitus

A Abdullah, P Biswas, M Sahabuddin… - Journal of …, 2023 - Wiley Online Library
Diabetes mellitus is a chronic hormonal and metabolic disorder in which our body cannot
generate necessary insulin or does not act in response to it, accordingly, ensuing in …

Specificity proteins (SP) and cancer

S Safe - International Journal of Molecular Sciences, 2023 - mdpi.com
The specificity protein (Sp) transcription factors (TFs) Sp1, Sp2, Sp3 and Sp4 exhibit
structural and functional similarities in cancer cells and extensive studies of Sp1 show that it …

Pulmonary delivery of curcumin and quercetin nanoparticles for lung cancer–Part 2: toxicity and endocytosis

CY Loo, D Traini, PM Young, T Parumasivam… - Journal of Drug Delivery …, 2023 - Elsevier
The delivery of polyphenol compounds via inhalation to treat lung cancer is attractive to
enable high drug concentration in the tumor cells. Although polyphenols such as curcumin …