[HTML][HTML] Study of MDM2 as Prognostic Biomarker in Brain-LGG Cancer and Bioactive Phytochemicals Inhibit the p53-MDM2 Pathway: A Computational Drug …
P Biswas, S Bibi, Q Yousafi, A Mehmood, S Saleem… - Molecules, 2023 - mdpi.com
An evaluation of the expression and predictive significance of the MDM2 gene in brain lower-
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
Molecular Dynamics Simulation and Pharmacoinformatic Integrated Analysis of Bioactive Phytochemicals from Azadirachta indica (Neem) to Treat Diabetes Mellitus
A Abdullah, P Biswas, M Sahabuddin… - Journal of …, 2023 - Wiley Online Library
Diabetes mellitus is a chronic hormonal and metabolic disorder in which our body cannot
generate necessary insulin or does not act in response to it, accordingly, ensuing in …
generate necessary insulin or does not act in response to it, accordingly, ensuing in …
Unraveling the signaling mechanism behind astrocytoma and possible therapeutics strategies: a comprehensive review
CL Nahar Metu, SK Sutihar, M Sohel, F Zohora… - Cancer …, 2023 - Wiley Online Library
Background A form of cancer called astrocytoma can develop in the brain or spinal cord and
sometimes causes death. A detailed overview of the precise signaling cascade underlying …
sometimes causes death. A detailed overview of the precise signaling cascade underlying …
WGS-based screening of the co-chaperone protein DjlA-induced curved DNA binding protein A (CbpA) from a new multidrug-resistant zoonotic mastitis-causing …
MH Rahman, S Al Azad, MF Uddin, M Farzana… - Molecular Diversity, 2023 - Springer
The research aimed to establish a multidrug-resistant Klebsiella pneumoniae-induced
genetic model for mastitis considering the alternative mechanisms of the DjlA-mediated …
genetic model for mastitis considering the alternative mechanisms of the DjlA-mediated …
[HTML][HTML] The Role of Oxidative Stress in Tumorigenesis and Progression
K Li, Z Deng, C Lei, X Ding, J Li, C Wang - Cells, 2024 - mdpi.com
Oxidative stress refers to the imbalance between the production of reactive oxygen species
(ROS) and the endogenous antioxidant defense system. Its involvement in cell senescence …
(ROS) and the endogenous antioxidant defense system. Its involvement in cell senescence …
Pulmonary delivery of curcumin and quercetin nanoparticles for lung cancer–Part 2: toxicity and endocytosis
CY Loo, D Traini, PM Young, T Parumasivam… - Journal of Drug Delivery …, 2023 - Elsevier
The delivery of polyphenol compounds via inhalation to treat lung cancer is attractive to
enable high drug concentration in the tumor cells. Although polyphenols such as curcumin …
enable high drug concentration in the tumor cells. Although polyphenols such as curcumin …
Biflavonoid quercetin protects against cyclophosphamide–induced organ toxicities via modulation of inflammatory cytokines, brain neurotransmitters, and astrocyte …
AY Onaolapo, FO Ojo, OJ Onaolapo - Food and chemical toxicology, 2023 - Elsevier
Background Cyclophosphamide use has been associated with increased oxidative stress in
cells and tissues. Quercetin's antioxidative properties make it of potential benefit in such …
cells and tissues. Quercetin's antioxidative properties make it of potential benefit in such …
[HTML][HTML] 20-Hydroxyecdysone confers antioxidant and antineoplastic properties in human non-small cell lung cancer cells
O Shuvalov, Y Kirdeeva, E Fefilova, S Netsvetay… - Metabolites, 2023 - mdpi.com
20-Hydroxyecdysone (20E) is an arthropod hormone which is synthesized by some plants
as part of their defense mechanism. In humans, 20E has no hormonal activity but possesses …
as part of their defense mechanism. In humans, 20E has no hormonal activity but possesses …
[HTML][HTML] A potential strategy against clinical carbapenem-resistant Enterobacteriaceae: antimicrobial activity study of sweetener-decorated gold nanoparticles in vitro …
H Liu, Z Huang, H Chen, Y Zhang, P Yu, P Hu… - Journal of …, 2023 - Springer
Abstract Background Carbapenem-resistant Enterobacteriaceae (CRE) present substantial
challenges to clinical intervention, necessitating the formulation of novel antimicrobial …
challenges to clinical intervention, necessitating the formulation of novel antimicrobial …
[HTML][HTML] New trends in microbial lipid-based biorefinery for fermentative bioenergy production from lignocellulosic biomass
S Al Azad, M Madadi, G Song, C Sun… - Biofuel Research …, 2024 - biofueljournal.com
Using oleaginous microbial lipid-based biorefinery from lignocellulosic biomass (LCB) to
produce fermentative bioenergy (ie, biodiesel) represents an innovative second-generation …
produce fermentative bioenergy (ie, biodiesel) represents an innovative second-generation …