The potential for senotherapy as a novel approach to extend life quality in veterinary medicine

ZJ Williams, L Chow, S Dow… - Frontiers in Veterinary …, 2024 - frontiersin.org
Cellular senescence, a condition where cells undergo arrest and can assume an
inflammatory phenotype, has been associated with initiation and perpetuation of …

[HTML][HTML] Molecular identification, characterization, and antagonistic activity profiling of Bacillus cereus LOCK 1002 along with the in-silico analysis of its presumptive …

S Islam, M Farjana, MR Uddin, S Akter… - Journal of Advanced …, 2022 - ncbi.nlm.nih.gov
Objectives: This research aimed to isolate, identify, and characterize a new strain of Bacillus
cereus through different molecular biology approaches so that it could be further studied for …

[HTML][HTML] Breaking down resistance: Verapamil analogues augment the efficacy of antibiotics against Streptococcus pneumoniae via MATE transporter interference

N Ahmed, P Biswas, MR Mogal, MR Sarker… - Informatics in Medicine …, 2024 - Elsevier
Pneumonia, an infectious lung disease, is a significant global health concern, claiming the
lives of 740,180 children in 2019, which accounts for 14% of pediatric deaths. Recently, the …

Exploring the potential of chromone scaffold compounds in cancer therapy: targeting key kinase pathways

R Islam, MS Hossain, PY Mock, SW Leong… - Medicinal Chemistry …, 2023 - Springer
Cancer continues to be one of the leading causes of death worldwide, with an estimated
28.4 million new cases expected by 2040. Despite the efforts to treat cancer, the current …

A comprehensive identification of potential molecular targets and small drugs candidate for melanoma cancer using bioinformatics and network-based screening …

DA Khan, T Adhikary, MT Sultana… - Journal of Biomolecular …, 2023 - Taylor & Francis
Melanoma is the third most common malignant skin tumor and has increased in morbidity
and mortality over the previous decade due to its rapid spread into the bloodstream or …

[HTML][HTML] HIF-1α promotes paraquat induced acute lung injury and implicates a role NF-κB and Rac2 activity

Y Zhu, X Meng, W Yang, J Wang, J Zhang, R Tian… - Toxicology, 2023 - Elsevier
Paraquat (PQ) is a bipyridine herbicide and oral exposure is the main way of PQ exposure
with a very high mortality. At present, it is believed that large number of oxygen free radicals …

Studies on the Requirement of Transthyretin Protein (BxTTR-52) for the Suppression of Host Innate Immunity in Bursaphelenchus xylophilus

TY Wen, Y Zhang, XQ Wu, JR Ye, YJ Qiu… - International Journal of …, 2022 - mdpi.com
The pinewood nematode, Bursaphelenchus xylophilus, has been determined as one of the
world's top ten plant-parasitic nematodes. It causes pine wilt, a progressive disease that …

[PDF][PDF] Research Progress on the Anti-tumor Effects of Euphorbia Humifusa

Z Wang, S Wu - Clin Onco., 2024 - clinicsofoncology.org
Euphorbia Humifusa is commonly known as ground spurge, contains various compounds
such as flavonoids, triterpenes, coumarins, sterols, tannins, and phenolic acids. It exerts a …

Serological and oncoinformatic analysis of HbA1c as a prognostic biomarker in screening the risks of different cancers among the male T2D patients of Bangladesh

M Al Hasibuzzaman, S Al Azad, MAR Mia, S Islam… - 2022 - preprints.org
This research aimed to figure out the applications of HbA1c protein and HbA1 gene as the
prognostic biomarkers for assessing the risks of different cancers among male T2D patients …

Esculetin unveiled: Decoding its anti‐tumor potential through molecular mechanisms—A comprehensive review

M Rezoan Hossain, FT Zahra Shova, M Akter… - Cancer …, 2024 - Wiley Online Library
Background The growing complexity of cancer has made it a significant concern in the
medical community. Although cancer research has advanced, it is still challenging to create …