Hypothermic machine perfusion of kidneys retrieved from standard and high‐risk donors

I Jochmans, JM O'Callaghan, J Pirenne… - Transplant …, 2015 - Wiley Online Library
Hypothermic machine perfusion (HMP) of kidneys is a long‐established alternative to static
cold storage and has been suggested to be a better preservation method. Today, as our …

[HTML][HTML] Kidney perfusion as an organ quality assessment tool—are we counting our chickens before they have hatched?

J De Beule, I Jochmans - Journal of Clinical Medicine, 2020 - mdpi.com
The final decision to accept an organ for transplantation remains a subjective one. With
“poor organ quality” commonly cited as a major reason for kidney discard, accurate …

Hypothermic machine perfusion in kidney transplantation

J De Deken, P Kocabayoglu… - Current opinion in organ …, 2016 - journals.lww.com
HMP has proven to be beneficial as a kidney preservation method for all types of renal
grafts, most notably those retrieved from extended criteria donors. Large numbers of …

[HTML][HTML] A review of current and emerging trends in donor graft-quality assessment techniques

N Warmuzińska, K Łuczykowski, B Bojko - Journal of Clinical Medicine, 2022 - mdpi.com
The number of patients placed on kidney transplant waiting lists is rapidly increasing,
resulting in a growing gap between organ demand and the availability of kidneys for …

[HTML][HTML] Assessing kidney graft viability and its cells metabolism during machine perfusion

MI Bellini, F Tortorici, MI Amabile… - International Journal of …, 2021 - mdpi.com
Kidney transplantation is the golden treatment for end-stage renal disease. Static cold
storage is currently considered the standard method of preservation, but dynamic …

[HTML][HTML] Ischemia-reperfusion injuries assessment during pancreas preservation

T Prudhomme, JF Mulvey, LAJ Young… - International Journal of …, 2021 - mdpi.com
Maintaining organ viability between donation and transplantation is of critical importance for
optimal graft function and survival. To date in pancreas transplantation, static cold storage …

The effect of the use of a TNF-alpha inhibitor in hypothermic machine perfusion on kidney function after transplantation

P Diuwe, P Domagala, M Durlik, J Trzebicki… - Contemporary Clinical …, 2017 - Elsevier
One of the most important problems in transplantation medicine is the ischemia/reperfusion
injury of the organs to be transplanted. The aim of the present study was to assess the effect …

[HTML][HTML] Advances in hypothermic and normothermic perfusion in kidney transplantation

TB Smith, ML Nicholson, SA Hosgood - Transplantology, 2021 - mdpi.com
Hypothermic and normothermic machine perfusion in kidney transplantation are purported
to exert a beneficial effect on post-transplant outcomes compared to the traditionally used …

Hypothermic oxygenated perfusion (HOPE) attenuates ischemia/reperfusion injury in the liver through inhibition of the TXNIP/NLRP3 inflammasome pathway in a rat …

W He, S Ye, C Zeng, S Xue, X Hu, X Zhang… - The FASEB …, 2018 - Wiley Online Library
Hypothermic oxygenated perfusion (HOPE) is a relatively new dynamic preservation
procedure that has not been widely implemented in liver transplantation despite its …

Role of temperature in reconditioning and evaluation of cold preserved kidney and liver grafts

T Minor, C von Horn, A Paul - Current Opinion in Organ …, 2017 - journals.lww.com
Machine perfusion after conventional cold storage is beneficial for ulterior function after
transplantation. Cold grafts should be initially perfused at low temperatures allowing for …