Sepsis remains a leading cause of death worldwide, despite advances in critical care, and
understanding of the pathophysiology and treatment strategies. No specific therapy or drugs …

Neutrophils are best known for their critical role in host defense, for which they utilize
multiple innate immune mechanisms, including microbe-associated pattern recognition …

Viral respiratory infections are a common cause of severe disease, especially in infants,
people who are immunocompromised, and in the elderly. Neutrophils, an important innate …

Sepsis, a common and potentially fatal systemic illness, is triggered by microbial infection
and often leads to impaired function of the lungs, kidneys or other vital organs. Since the …

Background Sepsis is a prevalent condition among hospitalized patients that carries a high
risk of morbidity and mortality. Rapid recognition of sepsis as the cause of deterioration is …

Sepsis remains a leading cause of death in critically ill patients, despite efforts to improve
patient outcome. Thus far, no magic drugs exist for severe sepsis and septic shock. Instead …

Sepsis is a clinical syndrome defined by physiologic changes indicative of systemic
inflammation, which are likely attributable to documented or suspected infection. Septic …

Biomarkers have great potential to improve the diagnosis and treatment of sepsis. The
available literature supports the potential utility of sTREM-1, IL-27, suPAR, neutrophil CD64 …

Sepsis is one of the leading causes of mortality and morbidity, even with the current
availability of extended-spectrum antibiotics and advanced medical care. Biomarkers offer a …

Background In resource limited settings acute febrile illnesses are often treated empirically
due to a lack of reliable, rapid point-of-care diagnostics. This contributes to the …