An association of serotonin with pain disorders and its modulation by estrogens

S Paredes, S Cantillo, KD Candido… - International journal of …, 2019 - mdpi.com
Ovarian hormones play an important role in pain perception, and are responsible, at least in
part, for the pain threshold differences between the sexes. Modulation of pain and its …

[HTML][HTML] Phenotypic features of central sensitization

DA Williams - Journal of applied biobehavioral research, 2018 - ncbi.nlm.nih.gov
Methods The manuscript covers the concept of diagnostic phenotyping, use of
endophenotypes, biomarkers, and symptom clusters. Specifically, the components of CS that …

Effects of acupuncture treatment on fibromyalgia symptoms, serotonin, and substance P levels: a randomized sham and placebo-controlled clinical trial

S Karatay, SC Okur, H Uzkeser, K Yildirim… - Pain …, 2018 - academic.oup.com
Objective The aim of this study was to evaluate the effects of acupuncture treatment on
serum levels of serotonin and substance P (SP) as well as on clinical parameters in patients …

Melatonin plus folic acid treatment ameliorates reserpine-induced fibromyalgia: An evaluation of pain, oxidative stress, and inflammation

R Fusco, R Siracusa, R D'Amico, AF Peritore… - Antioxidants, 2019 - mdpi.com
Background: Fibromyalgia is a chronic condition characterized by increased sensory
perception of pain, neuropathic/neurodegenerative modifications, oxidative, and nitrosative …

Differences in multidisciplinary and interdisciplinary treatment programs for fibromyalgia: a mapping review

EM Giusti, G Castelnuovo… - Pain research and …, 2017 - Wiley Online Library
Fibromyalgia is a multifaceted chronic pain syndrome and the integration of different health
disciplines is strongly recommended for its care. The interventions based on this principle …

Evidence that dry eye represents a chronic overlapping pain condition

AE Levitt, A Galor, AR Chowdhury, ER Felix… - Molecular …, 2017 - journals.sagepub.com
Recent data suggest that corneal somatosensory dysfunction may be the underlying cause
of severe dry eye symptoms in the absence of ocular surface pathology seen in a subset of …

[HTML][HTML] Inflammatory biochemical mediators and their role in myofascial pain and osteopathic manipulative treatment: a literature review

BT Leicht, C Kennedy, C Richardson - Cureus, 2022 - ncbi.nlm.nih.gov
Chronic inflammatory pain conditions, specifically myofascial pain (MFP), account for an
overwhelming percentage of office visits every day. The combination of the high cost of its …

Potential drug therapies for the treatment of fibromyalgia

K Lawson - Expert opinion on investigational drugs, 2016 - Taylor & Francis
Introduction: Fibromyalgia (FM) is a common, complex chronic widespread pain condition is
characterized by fatigue, sleep disturbance and cognitive dysfunction. Treatment of FM is …

[HTML][HTML] Serum calcitonin gene-related peptide and receptor protein levels in patients with fibromyalgia syndrome: A cross-sectional study

RU Korucu, A Karadağ, TAŞ Ayça… - Archives of …, 2020 - ncbi.nlm.nih.gov
Serum Calcitonin Gene-Related Peptide and Receptor Protein Levels in Patients With
Fibromyalgia Syndrome: A Cross-Sectional Study - PMC Back to Top Skip to main content NIH …

Effects of intravenous administration of recombinant Phα1β toxin in a mouse model of fibromyalgia

MPG Mendes, DC Dos Santos, MJS Rezende… - Toxicon, 2021 - Elsevier
This study investigated the effects of intravenous (iv) administration of recombinant Phα1β
toxin, pregabalin, and diclofenac by the intrathecal route using an animal model …