[HTML][HTML] Characterization of coacervation behavior between whey protein isolate and propylene glycol alginate: A morphology, spectroscopy, and thermodynamics …

C Xi, Z Sun, X Chen, X Ding, T Zhang - Food Chemistry: X, 2022 - Elsevier
The interactions between whey protein isolate (WPI) and propylene glycol alginate (PGA)
were investigated as a function of pH and the mass ratio. The results showed that WPI and …

Current research on polyelectrolyte nanostructures: from molecular interactions to biomedical applications

A Papagiannopoulos - Macromol, 2021 - mdpi.com
Polyelectrolytes have been at the center of interdisciplinary research for many decades. In
the field of polymer science and soft matter, they have provided the dimensions of …

Structure and dynamics of hybrid colloid–polyelectrolyte coacervates: Insights from molecular simulations

B Yu, H Liang, PF Nealey, MV Tirrell… - …, 2023 - ACS Publications
Electrostatic interactions in polymeric systems are responsible for a wide range of liquid–
liquid phase transitions that are of importance for biology and materials science. Such …

Influence of charge regulation and charge heterogeneity on complexation between polyelectrolytes and proteins

R Samanta, A Halabe, V Ganesan - The Journal of Physical …, 2020 - ACS Publications
We employed a combination of single chain in mean field methodology and constant pH
Monte Carlo framework to compare the influence of charge regulation and charge …

pH-induced complex coacervation of Gel and Agar: Phase behavior and structural properties

G Zhang, Y Wang, P Cui, Y Qiu, S Ye, A Zhang - Process Biochemistry, 2024 - Elsevier
In this study, we investigated the behavioral patterns of gelatin (Gel) and Agar in terms of
composites and phase separation. As the pH (4.5–7.0) increased, the electrostatic …

Encapsulating melittin from animal venom by finely tuned charge compensation with polymer carriers

Z Černochová, V Lobaz, L Čtveráčková… - European Polymer …, 2023 - Elsevier
Due to their wide availability, polypeptide/protein venoms produced by certain insects are of
high interest as potential active pharmacological ingredients; however, the number of …

“Mirror”-like protein dimers stabilized by local heterogeneity at protein surfaces

B Qiao, L Lopez… - The Journal of Physical …, 2019 - ACS Publications
Protein aggregation has been observed inside cells and holds true for membraneless
organelles. The precise understanding of protein dimerization is a prerequisite for …

Direct simulations of phase behavior of mixtures of oppositely charged proteins/nanoparticles and polyelectrolytes

R Samanta, V Ganesan - The Journal of Physical Chemistry B, 2020 - ACS Publications
We use direct simulations of particle–polyelectrolyte mixtures using the single chain in mean
field framework to extract the phase diagram for such systems. At high charges of the …

Tuning net charge in aliphatic polycarbonates alters solubility and protein complexation behavior

ND Posey, Y Ma, M Lueckheide, J Danischewski… - ACS …, 2021 - ACS Publications
A synthetic strategy yielded polyelectrolytes and polyampholytes with tunable net charge for
complexation and protein binding. Organocatalytic ring-opening polymerizations yielded …

Exploring protein-mediated compaction of DNA by coarse-grained simulations and unsupervised learning

M de Jager, PJ Kolbeck, W Vanderlinden, J Lipfert… - bioRxiv, 2024 - biorxiv.org
Protein-DNA interactions and protein-mediated DNA compaction play key roles in a range of
biological processes. The length scales typically involved in DNA bending, bridging …