Ribosome-inactivating proteins (RIPs) are mainly present in plants and function to inhibit
protein synthesis through the removal of adenine residues from eukaryotic ribosomal RNA …

Ribosome-inactivating proteins (RIPs) are toxins that act as N-glycosidases (EC 3.2. 2.22).
They are mainly produced by plants and classified as type 1 RIPs and type 2 RIPs. There …

While spinal microglia play a role in early stages of neuropathic pain etiology, whether they
are useful targets to reverse chronic pain at late stages remains unknown. Here, we show …

Ribosome-inactivating proteins (RIPs) are rRNA N-glycosylases from plants (EC 3.2. 2.22)
that inactivate ribosomes thus inhibiting protein synthesis. The antiviral properties of RIPs …

Thirty years ago, the type 1 ribosome-inactivating protein (RIP) saporin-S6 (also known as
saporin) was isolated from Saponaria officinalis L. seeds. Since then, the properties and …

Dwarf elder (Sambucus ebulus L) is one of the best known medicinal herbs since ancient
times. In view of its benefits as a widely applicable phytomedicine, it is still used in folk …

Immunotoxins are chimeric proteins obtained by linking a toxin to either an intact antibody or
an antibody fragment. Conjugation can be obtained by chemical or genetic engineering …

The term ribosome-inactivating protein (RIP) is used to denominate proteins mostly of plant
origin, which have N-glycosidase enzymatic activity leading to a complete destruction of the …

Biologically active plant peptides, consisting of secondary metabolites, are compounds
(amino acids) utilized by plants in their defense arsenal. Enzymatic processes and metabolic …

Molecular farming in plants is an emerging platform for the production of pharmaceutical
proteins, and host species such as tobacco are now becoming competitive with …