Kidney stone disease is one of the oldest diseases known to medicine; however, the
mechanisms of stone formation and development remain largely unclear. Over the past …

We have reviewed the general mechanisms involved in kidney stone formation, with
reference to those composed of calcium oxalate or phosphate, uric acid, and cystine. These …

Background Kidney stone disease (KSD) is a common illness that causes an economic
burden globally. It is easy for patients to relapse once they have suffered from this disease …

The pathophysiology of urinary stone formation is complex, involving a combination of
metabolic, genetic, and environmental factors. Over the past decades, remarkable advances …

Nephrolithiasis is an increasingly prevalent condition, especially in high income countries,
and is associated with high morbidity. Extraordinary progress in genetics made the …

Context Nephrocalcinosis (NC) and nephrolithiasis (NL) are described in
hypophosphatemic rickets, but data regarding their prevalence rates and the presence of …

Phosphate is an integral part of human cellular structure and function. Though most
recognised disorders of phosphaturia are genetic in origin, phosphate loss due to acquired …

OBJECTIVES: To assess the influence of hypertension on urinary metabolites as well as
recurrent stone formation. Recent studies have suggested that urolithiasis and hypertension …

Purpose This study aimed to accurately analyze the relationship between calcium oxalate
(CaOx) stone formation and the components of urinary nanocrystallites. Method High …

Urolithiasis is a multifaceted and common urological disorder characterized by the
development of renal calculi. Calcium oxalate stones are the most prevalent type of calculi …