The cerebrospinal fluid (CSF) is a complex solution that circulates around the CNS, and
whose composition changes as a function of an animal's physiological state. Ciliated …

Parkinson's disease (PD) is the second most common neurodegenerative disease, with
symptoms such as tremor, bradykinesia with rigidity, and depression appearing in the late …

Abstract Background α‐Synuclein (αSyn) is believed to play a central role in Parkinson's
disease (PD) neuropathology and is considered a target for disease modification. UB‐312 is …

Background Dementia is a prevalent non-motor manifestation among individuals with
advanced Parkinson's disease (PD). Glial fibrillary acidic protein (GFAP) is an inflammatory …

There is a pressing need for disease-modifying therapies in patients suffering from
neurodegenerative diseases, including Parkinson's disease (PD). However, these disorders …

Background Reliable and sensitive biomarkers are needed for enhancing and predicting
Parkinson's disease (PD) diagnosis. Objective To investigate comprehensive metabolomic …

Metabolomics samples like human urine or serum contain upwards of a few thousand
metabolites, but individual analytical techniques can only characterize a few hundred …

Amyloid plaques and tau tangles are pathological hallmarks of Alzheimer's disease (AD).
Parkinson's disease (PD) results from the accumulation of α-synuclein. TAR DNA-binding …

Biomarkers in Parkinson's disease are widely researched in the field of neuropsychiatry.
Though Parkinson's disease is diagnosed clinically, biomarkers prove to be a promising …

To date, the diagnoses of Parkinson syndromes are based on clinical examination.
Therefore, these specific diagnoses are made, when the neuropathological process is …