Hirsutine, an emerging natural product with promising therapeutic benefits: a systematic review
Fruits and vegetables are used not only for nutritional purposes but also as therapeutics to
treat various diseases and ailments. These food items are prominent sources of …
treat various diseases and ailments. These food items are prominent sources of …
Bacterial extracellular vesicles: an emerging avenue to tackle diseases
J Xie, F Haesebrouck, L Van Hoecke… - Trends in …, 2023 - cell.com
A growing body of research, especially in recent years, has shown that bacterial
extracellular vesicles (bEVs) are one of the key underlying mechanisms behind the …
extracellular vesicles (bEVs) are one of the key underlying mechanisms behind the …
The effect of combined treatment of psilocybin and eugenol on lipopolysaccharide-induced brain inflammation in mice
T Zanikov, M Gerasymchuk, E Ghasemi Gojani… - Molecules, 2023 - mdpi.com
Inflammation is an organism's biological defense mechanism. Acute and chronic
inflammation of the body triggers the production of pro-and anti-inflammatory pathways that …
inflammation of the body triggers the production of pro-and anti-inflammatory pathways that …
Distinguishing the effects of systemic CSF1R inhibition by PLX3397 on microglia and peripheral immune cells
Microglia, the primary immune cells of the central nervous system (CNS), are derived from
the yolk sac and populate the brain during development. Once microglia migrate to the CNS …
the yolk sac and populate the brain during development. Once microglia migrate to the CNS …
Lipopolysaccharides (LPSs) as potent neurotoxic glycolipids in Alzheimer's disease (AD)
Y Zhao, VR Jaber, AI Pogue, NM Sharfman… - International Journal of …, 2022 - mdpi.com
Lipopolysaccharides (LPSs) are microbiome-derived glycolipids that are among the most
potent pro-inflammatory neurotoxins known. In Homo sapiens, the major sources of LPSs …
potent pro-inflammatory neurotoxins known. In Homo sapiens, the major sources of LPSs …
Chlorogenic acid ameliorated non-alcoholic steatohepatitis via alleviating hepatic inflammation initiated by LPS/TLR4/MyD88 signaling pathway
X Gu, M Wei, F Hu, H Ouyang, Z Huang, B Lu… - Chemico-Biological …, 2023 - Elsevier
Non-alcoholic steatohepatitis (NASH) is a severe pathological stage in non-alcoholic fatty
liver disease (NAFLD) and is generally recognized to be induced by chronic inflammation …
liver disease (NAFLD) and is generally recognized to be induced by chronic inflammation …
Imaging quantitative changes in blood-brain barrier permeability using [18F]2-fluoro-2-deoxy-sorbitol ([18F]FDS) PET in relation to glial cell recruitment in a mouse …
S Leterrier, S Goutal, G Hugon… - Journal of Cerebral …, 2024 - journals.sagepub.com
The quantitative relationship between the disruption of the blood-brain barrier (BBB) and the
recruitment of glial cells was explored in a mouse model of endotoxemia.[18F] 2-Fluoro-2 …
recruitment of glial cells was explored in a mouse model of endotoxemia.[18F] 2-Fluoro-2 …
Intracerebral nanoparticle transport facilitated by alzheimer pathology and age
Nanoparticles have emerged as potential transporters of drugs targeting Alzheimer's
disease (AD), but their design should consider the blood–brain barrier (BBB) integrity and …
disease (AD), but their design should consider the blood–brain barrier (BBB) integrity and …
Lutein Encapsulated in PLGA–Phospholipid Nano-Carrier Effectively Mitigates Cytokines by Inhibiting Tumor Necrosis Factor TNF-α and Nuclear Factor NF-κB in …
R Arunkumar, V Baskaran - Journal of Functional Biomaterials, 2023 - mdpi.com
Lutein, a photo-and thermo-labile macular pigment, prevents the retina from suffering ocular
inflammation with its antioxidant and anti-inflammatory activity. However, its biological …
inflammation with its antioxidant and anti-inflammatory activity. However, its biological …
The potential of natural oils to improve inflammatory bowel disease
Y Zhou, D Wang, H Duan, S Zhou, J Guo, W Yan - Nutrients, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory disorder that includes
ulcerative colitis (UC) and Crohn's disease (CD), the exact cause of which is still unknown …
ulcerative colitis (UC) and Crohn's disease (CD), the exact cause of which is still unknown …