Endogenous cardiotonic steroids: physiology, pharmacology, and novel therapeutic targets

AY Bagrov, JI Shapiro, OV Fedorova - Pharmacological reviews, 2009 - ASPET
Endogenous cardiotonic steroids (CTS), also called digitalis-like factors, have been
postulated to play important roles in health and disease for nearly half a century. Recent …

Salt, blood pressure and cardiovascular disease

FJ He, GA MacGregor - Current opinion in cardiology, 2007 - journals.lww.com
The evidence for universal salt reduction is strong, and reducing salt from the current intake
of 10–12 g/day to the recommended level of 5–6 g/day will have a major effect on blood …

Thirst and hydration: physiology and consequences of dysfunction

SN Thornton - Physiology & behavior, 2010 - Elsevier
The constant supply of oxygen and nutriments to cells (especially neurons) is the role of the
cardiovascular system. The constant supply of water (and sodium) for cardiovascular …

Dietary sodium restriction rapidly improves large elastic artery compliance in older adults with systolic hypertension

PE Gates, H Tanaka, WR Hiatt, DR Seals - Hypertension, 2004 - Am Heart Assoc
We determined the temporal effects of dietary sodium restriction on large elastic artery
compliance and systolic blood pressure (SBP) in 12 untreated, older (64±2 years) men and …

Arterial stiffness and hypertension: a two-way street?

SS Franklin - Hypertension, 2005 - Am Heart Assoc
Hypertension may produce arterial stiffening by both functional and structural mechanisms.
1 Acute and potentially reversible stiffening of the thoracic aorta and its branches occurs with …

[PDF][PDF] Leitlinie zur Diagnose und Behandlung der chronischen koronaren Herzerkrankung der Deutschen Gesellschaft für Kardiologie–Herz-und Kreislaufforschung …

R Dietz, B Rauch - Clinical Research in Cardiology, 2003 - dgpr.de
Diese Leitlinien enthalten Empfehlungen zur Prävention, Diagnostik, Indikation und
Gegenindikation für diagnostische und interventionelle Maßnahmen, Empfehlungen zu …

Endogenous digitalis: pathophysiologic roles and therapeutic applications

AY Bagrov, JI Shapiro - Nature clinical practice Nephrology, 2008 - nature.com
Endogenous digitalis-like factors, also called cardiotonic steroids, have been thought for
nearly half a century to have important roles in health and disease. The endogenous …

Should we restrict chloride rather than sodium?

MF McCarty - Medical hypotheses, 2004 - Elsevier
Low-salt diets have potential for prevention and treatment of hypertension, and may also
reduce risk for stroke, left ventricular hypertrophy, osteoporosis, renal stones, asthma …

Management of hypertension in the elderly patient

GS Stokes - Clinical interventions in aging, 2009 - Taylor & Francis
Hypertension in the elderly is associated with increased occurrence rates of sodium
sensitivity, isolated systolic hypertension, and 'white coat effect'. Arterial stiffness and …

Hypertension, kidney, and transgenics: a fresh perspective

LJ Mullins, MA Bailey, JJ Mullins - Physiological reviews, 2006 - journals.physiology.org
In this review, we outline the application and contribution of transgenic technology to
establishing the genetic basis of blood pressure regulation and its dysfunction. Apart from a …