Molecular and immune landscape of hepatocellular carcinoma to guide therapeutic decision making

R Dhanasekaran, H Suzuki, L Lemaitre, N Kubota… - Hepatology, 2023 - journals.lww.com
Liver cancer, primarily hepatocellular carcinoma (HCC), exhibits highly heterogeneous
histological and molecular aberrations across tumors and within individual tumor nodules …

[HTML][HTML] Prognostic nutritional index as a prognostic biomarker for gastrointestinal cancer patients treated with immune checkpoint inhibitors

L Zhang, W Ma, Z Qiu, T Kuang, K Wang, B Hu… - Frontiers in …, 2023 - frontiersin.org
Objective Our study represents the first meta-analysis conducted to evaluate the prognostic
utility of the baseline prognostic nutritional index (PNI) in patients with gastrointestinal …

[HTML][HTML] Development and validation of prognostic risk prediction models for hepatocellular carcinoma patients treated with immune checkpoint inhibitors based on a …

D Ma, M Liu, X Zhai, X Li, B Jin, Y Liu - Frontiers in Immunology, 2023 - frontiersin.org
Objective To identify the risk factors associated with prognosis in patients with hepatocellular
carcinoma (HCC) treated with immune checkpoint inhibitors (ICI) via meta-analysis. And to …

Prognostic biomarkers associated with immune checkpoint inhibitors in hepatocellular carcinoma

X Chen, L Kou, X Xie, S Su, J Li, Y Li - Immunology, 2024 - Wiley Online Library
The treatment of hepatocellular carcinoma (HCC), particularly advanced HCC, has been a
serious challenge. Immune checkpoint inhibitors (ICIs) are landmark drugs in the field of …

Objective response and progression-free survival contribute to prolong overall survival in atezolizumab plus bevacizumab treatment for unresectable hepatocellular …

K Tajiri, K Tsukada, Y Tokimitsu, Y Motofuji, K Kawai… - Oncology, 2024 - karger.com
Objective Response and Progression-Free Survival Contribute to Prolong Overall Survival in
Atezolizumab plus Bevacizumab Treatment for Unresectable Hepatocellular Carcinoma …

[HTML][HTML] Prognostic value of controlling nutritional status on clinical and survival outcomes in cancer patients treated with immunotherapy

J Zhang, M Li, L Zhang, T Kuang, J Yu, W Wang - Scientific Reports, 2023 - nature.com
Cancer is a leading cause of death globally. Immunotherapy has shown promise in treating
various types of cancer, but its effectiveness varies among patients. The Controlling …

[HTML][HTML] The predictive value of sarcopenia and myosteatosis in trans-arterial (chemo)-embolization treated HCC patients

J Long, X Zhang, W Mi, J Shi, H Ren, Q Wang - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Background: We conducted a meta-analysis to provide evidence-based results for the
predictive values of sarcopenia, skeletal muscle index, psoas muscle index and the …

Prognostic value of nutritional and inflammatory markers in patients with hepatocellular carcinoma who receive immune checkpoint inhibitors

C Liu, H Zhao, R Zhang, Z Guo… - Oncology …, 2023 - spandidos-publications.com
The emergence of immune checkpoint inhibitors (ICIs) has provided a new treatment option
for patients with hepatocellular carcinoma (HCC). However, further evaluation is needed for …

[HTML][HTML] Biomarkers predicting the efficacy of immune checkpoint inhibitors in hepatocellular carcinoma

R Qin, T Jin, F Xu - Frontiers in Immunology, 2023 - frontiersin.org
In recent years, immune checkpoint inhibitors (ICIs) have emerged as a transformative
approach in treating advanced hepatocellular carcinoma (HCC). Despite their success …

[HTML][HTML] Systemic and local immunosuppression in glioblastoma and its prognostic significance

AA Stepanenko, AO Sosnovtseva, MP Valikhov… - Frontiers in …, 2024 - frontiersin.org
The effectiveness of tumor therapy, especially immunotherapy and oncolytic virotherapy,
critically depends on the activity of the host immune cells. However, various local and …