Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases
Oligonucleotide-based therapies are advanced novel interventions used in the management
of various respiratory diseases such as asthma and Chronic Obstructive Pulmonary Disease …
of various respiratory diseases such as asthma and Chronic Obstructive Pulmonary Disease …
The potential of siRNA based drug delivery in respiratory disorders: Recent advances and progress
Lung diseases are the leading cause of mortality worldwide. The currently available
therapies are not sufficient, leading to the urgent need for new therapies with sustained anti …
therapies are not sufficient, leading to the urgent need for new therapies with sustained anti …
A microRNA-21–mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis
Chronic obstructive pulmonary disease (COPD) is the third leading cause of morbidity and
death worldwide. Inhalation of cigarette smoke (CS) is the major cause in developed …
death worldwide. Inhalation of cigarette smoke (CS) is the major cause in developed …
Nanoparticles in cancer treatment: opportunities and obstacles
R Awasthi, A Roseblade, PM Hansbro… - Current drug …, 2018 - ingentaconnect.com
In the United States, the estimated number of new cancer cases in 2018 will be approx. 1.7
million. Historically, combination chemotherapy has been the primary choice of treatment …
million. Historically, combination chemotherapy has been the primary choice of treatment …
Mechanisms and treatments for severe, steroid‐resistant allergic airway disease and asthma
Severe, steroid‐resistant asthma is clinically and economically important since affected
individuals do not respond to mainstay corticosteroid treatments for asthma. Patients with …
individuals do not respond to mainstay corticosteroid treatments for asthma. Patients with …
Nanoparticle delivery of microRNA-146a regulates mechanotransduction in lung macrophages and mitigates injury during mechanical ventilation
Mechanical ventilation generates injurious forces that exacerbate lung injury. These forces
disrupt lung barrier integrity, trigger proinflammatory mediator release, and differentially …
disrupt lung barrier integrity, trigger proinflammatory mediator release, and differentially …
Assessing the potential of liposomes loaded with curcumin as a therapeutic intervention in asthma
ZY Ng, JY Wong, J Panneerselvam… - Colloids and surfaces B …, 2018 - Elsevier
Curcumin a component of turmeric, which is derived from Curcuma longa is used as a
colouring agent and as a dietary spice for centuries. Extensive studies have been done on …
colouring agent and as a dietary spice for centuries. Extensive studies have been done on …
MicroRNAs as biomarker for breast cancer
Regardless of advances in detection and treatment, breast cancer affects about 1.5 million
women all over the world. Since the last decade, genome-wide association studies (GWAS) …
women all over the world. Since the last decade, genome-wide association studies (GWAS) …
[HTML][HTML] MicroRNAs as biological regulators in skin disorders
G Singhvi, P Manchanda, VK Rapalli, SK Dubey… - Biomedicine & …, 2018 - Elsevier
Abstract microRNAs are being investigated as promising therapeutic targets and biomarkers
for different disease conditions. miRNAs serve as essential regulators of cell differentiation …
for different disease conditions. miRNAs serve as essential regulators of cell differentiation …
The role of miR-214 in cardiovascular diseases
Y Zhao, M Ponnusamy, L Zhang, Y Zhang, C Liu… - European journal of …, 2017 - Elsevier
Cardiovascular disease (CVD) is the leading cause of death throughout the world. The
increase in new patients every year leads to a demand for the identification of valid and …
increase in new patients every year leads to a demand for the identification of valid and …