Epidemiology and immune pathogenesis of viral sepsis
GL Lin, JP McGinley, SB Drysdale… - Frontiers in …, 2018 - frontiersin.org
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection. Sepsis can be caused by a broad range of pathogens; however, bacterial …
infection. Sepsis can be caused by a broad range of pathogens; however, bacterial …
Metabolomics toward personalized medicine
M Jacob, AL Lopata, M Dasouki… - Mass spectrometry …, 2019 - Wiley Online Library
Metabolomics, which is the metabolites profiling in biological matrices, is a key tool for
biomarker discovery and personalized medicine and has great potential to elucidate the …
biomarker discovery and personalized medicine and has great potential to elucidate the …
The 2022 update of IUIS phenotypical classification for human inborn errors of immunity
A Bousfiha, A Moundir, SG Tangye, C Picard… - Journal of clinical …, 2022 - Springer
Abstract The International Union of Immunological Societies (IUIS) expert committee (EC) on
Inborn Errors of Immunity (IEI) reports here the 2022 updated phenotypic classification …
Inborn Errors of Immunity (IEI) reports here the 2022 updated phenotypic classification …
Human inborn errors of immunity: 2019 update of the IUIS phenotypical classification
A Bousfiha, L Jeddane, C Picard, W Al-Herz… - Journal of clinical …, 2020 - Springer
Abstract Since 2013, the International Union of Immunological Societies (IUIS) expert
committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic …
committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic …
The 2017 IUIS phenotypic classification for primary immunodeficiencies
A Bousfiha, L Jeddane, C Picard, F Ailal… - Journal of clinical …, 2018 - Springer
Since the 1990s, the International Union of Immunological Societies (IUIS) PID expert
committee (EC), now called Inborn Errors of Immunity Committee, has published every other …
committee (EC), now called Inborn Errors of Immunity Committee, has published every other …
Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations
J Thalhammer, G Kindle, A Nieters, S Rusch… - Journal of Allergy and …, 2021 - Elsevier
Background Inborn errors of immunity (IEI) are rare diseases, which makes diagnosis a
challenge. A better description of the initial presenting manifestations should improve …
challenge. A better description of the initial presenting manifestations should improve …
Global systematic review of primary immunodeficiency registries
Introduction During the last 4 decades, registration of patients with primary
immunodeficiencies (PID) has played an essential role in different aspects of these diseases …
immunodeficiencies (PID) has played an essential role in different aspects of these diseases …
The 2015 IUIS phenotypic classification for primary immunodeficiencies
A Bousfiha, L Jeddane, W Al-Herz, F Ailal… - Journal of clinical …, 2015 - Springer
There are now nearly 300 single-gene inborn errors of immunity underlying phenotypes as
diverse as infection, malignancy, allergy, auto-immunity, and auto-inflammation. For each of …
diverse as infection, malignancy, allergy, auto-immunity, and auto-inflammation. For each of …
Global report on primary immunodeficiencies: 2018 update from the Jeffrey Modell Centers Network on disease classification, regional trends, treatment modalities …
V Modell, JS Orange, J Quinn, F Modell - Immunologic research, 2018 - Springer
Primary immunodeficiencies (PI) are genetic defects of the immune system that result in
chronic, serious, and often life-threatening infections, if not diagnosed and treated. Many …
chronic, serious, and often life-threatening infections, if not diagnosed and treated. Many …
Tregopathies: monogenic diseases resulting in regulatory T-cell deficiency
Monogenic diseases of the immune system, also known as inborn errors of immunity, are
caused by single-gene mutations resulting in immune deficiency and dysregulation. More …
caused by single-gene mutations resulting in immune deficiency and dysregulation. More …