Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Quercetin, a naturally non-toxic flavonoid within the safe dose range with antioxidant, anti-
apoptotic and anti-inflammatory properties, plays an important role in the treatment of aging …

The discovery and interpretation of peroxisome proliferator-activated receptor γ coactivator
1α (PGC-1α) protein in mitochondrial biogenesis, skeletal muscle and adipose tissue …

Coronary artery disease (CAD) is the leading cause of death worldwide. Oxidative stress
and inflammation are major mechanisms responsible for the progression of CAD. Nuclear …

Mitochondria play a vital role in maintaining cellular energy homeostasis, regulating
apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated …

Sirtuins are a family of proteins with enzymatic activity. There are seven mammalian sirtuins
(SIRT1-SIRT7) that are found in different cellular compartments. They are a part of crucial …

Selenium (Se) is an essential dietary trace element that plays an important role in the
prevention of inflammation, cardiovascular diseases, infections, and cancer. Selenoproteins …

Intermittent fasting entails restricting food intake during specific times of day, days of the
week, religious practice, or surrounding clinically important events. Herein, the metabolic …

Chronic pain remains an unresolved problem. Current treatments have limited efficacy.
Thus, novel therapeutic targets are urgently required for the development of more effective …

In recent years, researchers have begun to realize the importance of the role of non-coding
RNAs in the treatment of cancer and cardiovascular and neurological diseases. LncRNAs …