The dimensional model of adversity proposes that experiences of threat and deprivation
have distinct neurodevelopmental consequences. We examined these dimensions …

The stressful extrauterine environment following premature birth likely has far-reaching and
persistent adverse consequences. The effects of early “third-trimester” ex utero stress on …

Socioeconomic disadvantage during childhood predicts an increased risk for mental health
problems across the lifespan. Socioeconomic disadvantage shapes multiple aspects of …

Understanding how traumatic stress affects typical brain development during adolescence is
critical to elucidate underlying mechanisms related to both maladaptive functioning and …

Early-life stress has pervasive, typically detrimental, effects on physical and mental health
across the lifespan. In rats, maternal-separation stress results in premature expression of an …

The developing brain is marked by high plasticity, which can lead to vulnerability to early life
stressors. Previous studies indicate that childhood maltreatment is associated with structural …

Psychosocial acceleration theory and other frameworks adapted from life history predict a
link between early life stress and accelerated maturation in several physiological systems …

Anhedonia, or diminished pleasure and motivation, is a symptom of severe mental illness
(eg, depressive disorder, bipolar disorder, schizophrenia) that emerges during adolescence …

Early life stress (ELS) may accelerate frontoamygdala development related to
socioemotional processing, serving as a potential source of resilience. Whether this circuit is …