Abstract Polygenic Risk Scores (PRS) are a major component of accurate breast cancer risk
prediction and have the potential to improve screening and prevention strategies. PRS …

Importance Risk prediction for coronary heart disease (CHD) is a cornerstone of primary
prevention strategies. Polygenic risk scores (PRSs) have emerged as a new approach to …

Since their first appearance in the context of schizophrenia and bipolar disorder in 2009,
polygenic risk scores (PRSs) have been described for a large number of common complex …

Polygenic scores (PGS) are important tools for carrying out genetic prediction of common
diseases and disease related complex traits, facilitating the development of precision …

Simple Summary Several risk prediction tools have been developed to better stratify women
according to their risk of developing breast cancer (BC) and inform prevention and early …

Advances in genomics have enabled the development of polygenic scores (PGS),
sometimes called polygenic risk scores, in the context of multifactorial diseases and …

A polygenic risk score (PRS) quantifies the aggregated effects of common genetic variants in
an individual. A 'personalised breast cancer risk assessment'combines PRS with other …

Simple Summary Various genomic variants that are statistically associated with breast
cancer (BC) have been discovered and robustly replicated as a result of different genome …

The proportion of lung cancer in never smokers is rising, especially among Asian women,
but there is no effective early detection tool. Here, we developed a polygenic risk score …

Genetic testing is performed more routinely in clinical practice, and direct-to-consumer tests
are widely available. It has obvious appeal as a preventive health measure. Clinicians and …