The autosomal dominant spinocerebellar ataxias (SCAs) are a heterogeneous group of
degenerative diseases of the cerebellum and connected regions. The discovery of various …

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant cerebellar ataxia that
occurs as a consequence of abnormal CAG expansions in the ATXN2 gene. Progressive …

Background The search for valid preclinical biomarkers of cerebellar dysfunction is a key
research goal for the upcoming era of early interventional approaches in spinocerebellar …

Background The cerebellar cognitive affective syndrome scale (CCAS-S) was recently
developed to detect specific neuropsychological deficits in patients with cerebellar diseases …

Eye movements in neurodegenerative diseases : Current Opinion in Neurology Eye
movements in neurodegenerative diseases : Current Opinion in Neurology Log in or Register …

Recent advances in understanding dominant spinocerebellar ataxias from clinical and
genetic points of view - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

The prevalence estimations of hereditary ataxias are biased since most epidemiological
studies are confined to isolated geographical regions and few nationwide studies are …

The cerebellar cognitive affective syndrome scale (CCAS-S) was designed to detect specific
cognitive dysfunctions in cerebellar patients but is scarcely validated in spinocerebellar …

Objective Spinocerebellar ataxia type 2 (SCA 2) is an autosomal dominantly inherited
neurodegenerative disease mainly affecting the cerebellum and brainstem. In this Cuban …

Highlights•Cognitive impairment in SCAs is well-established, but not universal in all
patients.•The CCAS Scale is the current standard for identifying cognitive impairments in …