Foam cells in atherosclerosis: novel insights into its origins, consequences, and molecular mechanisms
Y Gui, H Zheng, RY Cao - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Foam cells play a vital role in the initiation and development of atherosclerosis. This review
aims to summarize the novel insights into the origins, consequences, and molecular …
aims to summarize the novel insights into the origins, consequences, and molecular …
Role of lipid accumulation and inflammation in atherosclerosis: focus on molecular and cellular mechanisms
K Malekmohammad, EE Bezsonov… - Frontiers in …, 2021 - frontiersin.org
Atherosclerosis is a chronic lipid-driven and maladaptive inflammatory disease of arterial
intima. It is characterized by the dysfunction of lipid homeostasis and signaling pathways …
intima. It is characterized by the dysfunction of lipid homeostasis and signaling pathways …
[HTML][HTML] Molecularly targeted nanomedicine enabled by inorganic nanoparticles for atherosclerosis diagnosis and treatment
Atherosclerosis, a chronic cardiovascular disease caused by plaque development in
arteries, remains a leading cause of morbidity and mortality. Atherosclerotic plaques are …
arteries, remains a leading cause of morbidity and mortality. Atherosclerotic plaques are …
Inflammatory cells in atherosclerosis
M Mehu, CA Narasimhulu, DK Singla - Antioxidants, 2022 - mdpi.com
Atherosclerosis is a chronic progressive disease that involves damage to the intima,
inflammatory cell recruitment and the accumulation of lipids followed by calcification and …
inflammatory cell recruitment and the accumulation of lipids followed by calcification and …
Macrophages and foam cells: Brief overview of their role, linkage, and targeting potential in atherosclerosis
AV Poznyak, NG Nikiforov, AV Starodubova… - Biomedicines, 2021 - mdpi.com
Atherosclerosis is still one of the main causes of death around the globe. This condition
leads to various life-threatening cardiovascular complications. However, no effective …
leads to various life-threatening cardiovascular complications. However, no effective …
Perivascular adipose-derived exosomes reduce macrophage foam cell formation through miR-382-5p and the BMP4-PPARγ-ABCA1/ABCG1 pathways
Y Liu, Y Sun, X Lin, D Zhang, C Hu, J Liu, Y Zhu… - Vascular …, 2022 - Elsevier
Background Perivascular adipose tissue (PVAT) releases exosomes (EXOs) to regulate
vascular homeostasis. PVAT-derived EXOs reduce macrophage foam cell formation, but the …
vascular homeostasis. PVAT-derived EXOs reduce macrophage foam cell formation, but the …
Cholesterol in the cell membrane—an emerging player in atherogenesis
K Paukner, I Králová Lesná, R Poledne - International Journal of …, 2022 - mdpi.com
Membrane cholesterol is essential for cell membrane properties, just as serum cholesterol is
important for the transport of molecules between organs. This review focuses on cholesterol …
important for the transport of molecules between organs. This review focuses on cholesterol …
Evolving concepts in the pathophysiology of atherosclerosis: From endothelial dysfunction to thrombus formation through multiple shades of inflammation
Atherosclerosis is the anatomo-pathological substrate of most cardio, cerebro and vascular
diseases such as acute and chronic coronary syndromes, stroke and peripheral artery …
diseases such as acute and chronic coronary syndromes, stroke and peripheral artery …
PLK1 promotes cholesterol efflux and alleviates atherosclerosis by up-regulating ABCA1 and ABCG1 expression via the AMPK/PPARγ/LXRα pathway
HJ Hu, XH Wang, TQ Zhang, Y Liu, ZR Chen… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Abstract Polo-like kinase 1 (PLK1) is a serine/threonine kinase involving lipid metabolism
and cardiovascular disease. However, its role in atherogenesis has yet to be determined …
and cardiovascular disease. However, its role in atherogenesis has yet to be determined …
Canonical and non-canonical roles of complement in atherosclerosis
Cardiovascular diseases are the leading cause of death globally, and atherosclerosis is the
major contributor to the development and progression of cardiovascular diseases. Immune …
major contributor to the development and progression of cardiovascular diseases. Immune …