Polyphenols are an important component of plant-derived food with a wide spectrum of
beneficial effects on human health. For many years, they have aroused great interest …

Fruits, vegetables, and other food items contain phytochemicals or secondary metabolites
which may be considered non-essential nutrients but have medicinal importance. These …

The metabolic roadmap of drugs (MRD) is a comprehensive atlas for understanding the
stepwise and sequential metabolism of certain drug in living organisms. It plays a vital role in …

Butyrylcholinesterase (BChE) is present in plasma and numerous cells and organs. Its
physiological function (s) is (are) still unclear. However, this enzyme is of pharmacological …

This study investigates the mechanism by which butyric acid can protect against calcium
oxalate (CaOx) nephrolithiasis. To do so, a rat model was used with 0.75% ethylene glycol …

Quercetin is the most abundant polyphenolic flavonoid (flavonol subclass) in vegetal foods
and medicinal plants. This dietary chemopreventive agent has drawn significant interest for …

Arylacetamide deacetylase (AADAC) is involved in drug hydrolysis and lipid metabolism. In
23 human liver samples, no significant correlation was observed between AADAC mRNA …

Enzymes catalyzing the reduction reaction of xenobiotics are mainly members of the aldo-
keto reductase (AKR) and short-chain dehydrogenase/reductase (SDR) superfamilies. The …

The rise of multidrug-resistant bacteria underlines the need for innovative treatments, yet the
introduction of new drugs has stagnated despite numerous antimicrobial discoveries. A …

Mammalian cytochrome P450 drug‐metabolizing enzymes rarely cleave carbon–carbon (C−
C) bonds and the mechanisms of such cleavages are largely unknown. We identified two …