Endocannabinoid system and exogenous cannabinoids in depression and anxiety: a review

A Hasbi, BK Madras, SR George - Brain Sciences, 2023 - mdpi.com
Background: There is a growing liberalization of cannabis-based preparations for medical
and recreational use. In multiple instances, anxiety and depression are cited as either a …

Cannabinoids as medicinals

JH Khalsa, G Bunt, K Blum, SB Maggirwar… - Current addiction …, 2022 - Springer
Purpose of review There have been many debates, discussions, and published writings
about the therapeutic value of cannabis plant and the hundreds of cannabinoids it contains …

Development of an efficient yeast platform for cannabigerolic acid biosynthesis

Y Zhang, J Guo, PZ Gao, W Yan, J Shen, X Luo… - Metabolic …, 2023 - Elsevier
Cannabinoids are important therapeutical molecules for human ailments, cancer treatment,
and SARS-CoV-2. The central cannabinoid, cannabigerolic acid (CBGA), is generated from …

Cannabidiol alleviates neuroinflammation and attenuates neuropathic pain via targeting FKBP5

X Wang, C Lin, S Jin, Y Wang, Y Peng… - Brain, behavior, and …, 2023 - Elsevier
Microglia is a heterogeneous population that mediates neuroinflammation in the central
nervous system (CNS) and plays a crucial role in developing neuropathic pain. FKBP5 …

Endocannabinoid system: chemical characteristics and biological activity

B Rezende, AKN Alencar, GF de Bem… - Pharmaceuticals, 2023 - mdpi.com
The endocannabinoid system (eCB) has been studied to identify the molecular structures
present in Cannabis sativa. eCB consists of cannabinoid receptors, endogenous ligands …

Cannabigerol (CBG) attenuates mechanical hypersensitivity elicited by chemotherapy‐induced peripheral neuropathy

DE Sepulveda, DP Morris… - … Journal of Pain, 2022 - Wiley Online Library
Background Cannabigerol (CBG) is a non‐psychoactive phytocannabinoid produced by the
plant Cannabis sativa with affinity to various receptors involved in nociception. As a result …

An individuality of response to cannabinoids: challenges in safety and efficacy of cannabis products

S Kitdumrongthum, D Trachootham - Molecules, 2023 - mdpi.com
Since legalization, cannabis/marijuana has been gaining considerable attention as a
functional ingredient in food.∆-9 tetrahydrocannabinol (THC), cannabidiol (CBD), and other …

The current role of cannabis and cannabinoids in health: A comprehensive review of their therapeutic potential

MP Coelho, P Duarte, M Calado, AJ Almeida, CP Reis… - Life Sciences, 2023 - Elsevier
There has been an increased interest of the scientific community in cannabis and its
constituents for therapeutic purposes. Although it is believed that cannabinoids can be …

Characterization of the biochemical and behavioral effects of cannabidiol: implications for migraine

R Greco, M Francavilla, C Demartini… - The journal of headache …, 2023 - Springer
Cannabidiol (CBD) is the main pharmacologically active phytocannabinoid. CBD exerts an
analgesic effect in several pain models, does not have side effects and has low toxicity. The …

Cannabidiol and cannabigerol, nonpsychotropic cannabinoids, as analgesics that effectively manage bone fracture pain and promote healing in mice

DK Khajuria, V Karuppagounder… - Journal of Bone and …, 2023 - academic.oup.com
Bone fractures are among the most prevalent musculoskeletal injuries, and pain
management is an essential part of fracture treatment. Fractures heal through an early …