Clinical neurology and epidemiology of the major neurodegenerative diseases

MG Erkkinen, MO Kim… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Neurodegenerative diseases are a common cause of morbidity and cognitive impairment in
older adults. Most clinicians who care for the elderly are not trained to diagnose these …

The prevalence and incidence of frontotemporal dementia: a systematic review

DB Hogan, N Jetté, KM Fiest, JI Roberts… - Canadian Journal of …, 2016 - cambridge.org
BackgroundPopulation-based prevalence and incidence studies are essential for
understanding the burden of frontotemporal dementia (FTD). MethodsThe MEDLINE and …

Epidemiology of aging and associated cognitive disorders: Prevalence and incidence of Alzheimer's disease and other dementias

OL Lopez, LH Kuller - Handbook of clinical neurology, 2019 - Elsevier
The study of the incidence and prevalence of dementia is important to understand the
distribution of dementing illness among age and sex groups, and for the detection of …

Fluid biomarkers in frontotemporal dementia: past, present and future

IJ Swift, A Sogorb-Esteve, C Heller… - Journal of Neurology …, 2021 - jnnp.bmj.com
The frontotemporal dementia (FTD) spectrum of neurodegenerative disorders includes a
heterogeneous group of conditions. However, following on from a series of important …

[HTML][HTML] Overview of therapeutic targets in management of dementia

R Malik, S Kalra, S Bhatia, A Al Harrasi, G Singh… - Biomedicine & …, 2022 - Elsevier
Dementia is defined as a gradual cognitive impairment that interferes with everyday tasks,
and is a leading cause of dependency, disability, and mortality. According to the current …

Optical coherence tomography reveals retinal neuroaxonal thinning in frontotemporal dementia as in Alzheimer's disease

L Ferrari, SC Huang, G Magnani… - Journal of …, 2017 - content.iospress.com
Background: Alzheimer's disease (AD) and frontotemporal dementia (FTD) are leading
causes of cognitive decline. Optical coherence tomography (OCT) allows the measurement …

Frontotemporal lobar degeneration: current perspectives

L Riedl, IR Mackenzie, H Förstl, A Kurz… - Neuropsychiatric …, 2014 - Taylor & Francis
The term frontotemporal lobar degeneration (FTLD) refers to a group of progressive brain
diseases, which preferentially involve the frontal and temporal lobes. Depending on the …

Tweaking progranulin expression: therapeutic avenues and opportunities

J Terryn, CM Verfaillie, P Van Damme - Frontiers in Molecular …, 2021 - frontiersin.org
Frontotemporal dementia (FTD) is a neurodegenerative disease, leading to behavioral
changes and language difficulties. Heterozygous loss-of-function mutations in progranulin …

Assessment of individuals with primary progressive aphasia

ML Henry, SM Grasso - Seminars in speech and language, 2018 - thieme-connect.com
Speech–language pathologists play a crucial role in the assessment and treatment of
individuals with primary progressive aphasia (PPA). The speech–language evaluation is a …

[HTML][HTML] Episodic and working memory function in Primary Progressive Aphasia: A meta-analysis

WS Eikelboom, N Janssen, LC Jiskoot… - Neuroscience & …, 2018 - Elsevier
Abstract Objective The distinction between Primary Progressive Aphasia (PPA) variants
remains challenging for clinicians, especially for the non-fluent (nfv-PPA) and the logopenic …