Assessing the multivariate relationship between the human infant intestinal exfoliated cell transcriptome (exfoliome) and microbiome in response to diet

K He, SM Donovan, IV Ivanov, JS Goldsby… - Microorganisms, 2020 - mdpi.com
Gut microbiota and the host exist in a mutualistic relationship, with the functional
composition of the microbiota strongly influencing the health and well-being of the host. In …

A membrane fusion protein αSNAP is a novel regulator of epithelial apical junctions

NG Naydenov, B Brown, G Harris, MR Dohn… - PloS one, 2012 - journals.plos.org
Tight junctions (TJs) and adherens junctions (AJs) are key determinants of the structure and
permeability of epithelial barriers. Although exocytic delivery to the cell surface is crucial for …

The POZ-ZF transcription factor Kaiso (ZBTB33) induces inflammation and progenitor cell differentiation in the murine intestine

R Chaudhary, CC Pierre, K Nanan, D Wojtal… - PLoS …, 2013 - journals.plos.org
Since its discovery, several studies have implicated the POZ-ZF protein Kaiso in both
developmental and tumorigenic processes. However, most of the information regarding …

p120-Catenin is an obligate haploinsufficient tumor suppressor in intestinal neoplasia

SP Short, J Kondo, WG Smalley-Freed… - The Journal of …, 2017 - Am Soc Clin Investig
p120-Catenin (p120) functions as a tumor suppressor in intestinal cancer, but the
mechanism is unclear. Here, using conditional p120 knockout in Apc-sensitized mouse …

EpCAM is essential for maintenance of the small intestinal epithelium architecture via regulation of the expression and localization of proteins that compose adherens …

G Chen, Y Yang, W Liu, L Huang… - International …, 2021 - spandidos-publications.com
Epithelial cell adhesion molecule (EpCAM) is highly expressed in mammalian intestines,
and is essential for maintaining the homeostasis of the intestinal epithelium. EpCAM protein …

p120-Catenin: a novel regulator of innate immunity and inflammation

G Hu - Critical Reviews™ in Immunology, 2012 - dl.begellhouse.com
ABSTRACT p120-Catenin is the prototypic member of a subfamily of armadillo repeat
domain proteins. Like its structural homologues, β-and γ-catenin, p120-catenin is an …

Capturing species‐wide diversity of the gut microbiota and its relationship with genomic variation in the critically endangered kākāpō

AG West, A Digby, AW Santure, JG Guhlin… - Molecular …, 2023 - Wiley Online Library
Gut microbiota play an essential role in host health with important implications for
conservation management of threatened wildlife. While factors such as diet, medication and …

[HTML][HTML] p120-catenin expressed in alveolar type II cells is essential for the regulation of lung innate immune response

AZ Chignalia, SM Vogel, AB Reynolds, D Mehta… - The American journal of …, 2015 - Elsevier
The integrity of the lung alveolar epithelial barrier is required for the gas exchange and is
important for immune regulation. Alveolar epithelial barrier is composed of flat type I cells …

Pro-tumorigenic phosphorylation of p120 catenin in renal and breast cancer

A Kourtidis, M Yanagisawa, D Huveldt, JA Copland… - PloS one, 2015 - journals.plos.org
Altered protein expression and phosphorylation are common events during malignant
transformation. These perturbations have been widely explored in the context of E-cadherin …

p120 Modulates LPS‐Induced NF‐κB Activation Partially through RhoA in Bronchial Epithelial Cells

L Qin, S Qin, Y Zhang, C Zhang, H Ma… - BioMed Research …, 2014 - Wiley Online Library
p120‐Catenin (p120) is an adherens junction protein recognized to regulate cell‐cell
adhesion. Emerging evidence indicates that p120 may also play an important role in …