Cirrhosis causes a heavy global burden. In this review, we summarized up-to-date
epidemiological features of cirrhosis and its complications. Recent epidemiological studies …

An understanding of connections between gut microbiome and liver has provided important
insights into the pathophysiology of liver diseases. Since gut microbial dysbiosis increases …

Portal hypertension is the cause of the clinical complications associated with cirrhosis. The
primary complications of portal hypertension are ascites, acute variceal bleed, and hepatic …

Background: Liver transplantation (LT) is associated with a significant risk of intraoperative
hemorrhage and massive blood transfusion. However, there are few relevant reports …

The development of refractory ascites in approximately 10% of patients with decompensated
cirrhosis heralds the progression to a more advanced stage of cirrhosis. Its pathogenesis is …

Chronic liver diseases (CLD) affect 1.5 billion patients worldwide, with dramatically
increasing incidence in recent decades. It has been hypothesized that the chronic …

Purpose The popularity of direct oral anticoagulants (DOACs) is increasing among patients
with cirrhosis. Cirrhosis has a major impact on the pharmacokinetics of drugs, potentially …

Background: Cirrhosis and end-stage kidney disease (ESKD) are significant global health
concerns, contributing to high mortality and morbidity. Haemodialysis (HD) is frequently …

Background Small intestinal bacterial overgrowth (SIBO) occurs frequently in patients with
cirrhosis, particularly in those with ascites, and promotes the translocation of gut-derived …

BACKGROUND The hemodynamic alterations seen in liver cirrhosis lead to renal
vasoconstriction, ultimately causing acute kidney injury (AKI). The renal resistive index (RRI) …