Chronic obstructive pulmonary disease in never-smokers: risk factors, pathogenesis, and implications for prevention and treatment

IA Yang, CR Jenkins, SS Salvi - The Lancet Respiratory Medicine, 2022 - thelancet.com
Chronic obstructive pulmonary disease (COPD) was traditionally thought to be caused by
tobacco smoking. However, recognition of the importance of non-smoking-related risk …

Non-coding RNAs in airway diseases: a brief overview of recent data

GD Albano, R Gagliardo, AM Montalbano, M Profita - Cancers, 2022 - mdpi.com
Simple Summary Nc-RNA are microRNA, long-coding RNA, and circulating-RNA. In this
review we report most recent data regarding the role of nc-RNA in airway diseases, with a …

Airway inflammatory changes in the lungs of patients with asthma-COPD overlap (ACO): a bronchoscopy endobronchial biopsy study

S Dey, W Lu, G Haug, C Chia, J Larby, HC Weber… - Respiratory …, 2023 - Springer
Background Although asthma and chronic obstructive pulmonary disease (COPD) are two
distinct chronic airway inflammatory diseases, they often co-exist in a patient and the …

Association of blood cadmium concentration with chronic obstructive pulmonary disease progression: a prospective cohort study

J Sun, YP Deng, J Xu, FM Zhu, QY He, MM Tang… - Respiratory …, 2024 - Springer
Background Prior studies in patients with chronic obstructive pulmonary disease (COPD)
had indicated a potential correlation between cadmium (Cd) exposure and reduction in lung …

Mendelian randomization study shows a causal effect of asthma on chronic obstructive pulmonary disease risk

Y Li, W Wang, D Zhou, Q Lu, L Li, B Zhang - Plos one, 2023 - journals.plos.org
Background This study was performed to explore the causal association between asthma
and chronic obstructive pulmonary disease (COPD). Methods We obtained summary …

Membrane adhesion junctions regulate airway smooth muscle phenotype and function

W Zhang, Y Wu, S J. Gunst - Physiological Reviews, 2023 - journals.physiology.org
The local environment surrounding airway smooth muscle (ASM) cells has profound effects
on the physiological and phenotypic properties of ASM tissues. ASM is continually subjected …

The role of eosinophil-derived neurotoxin and vascular endothelial growth factor in the pathogenesis of eosinophilic asthma

M Tota, J Łacwik, J Laska, Ł Sędek, K Gomułka - Cells, 2023 - mdpi.com
Asthma is a chronic complex pulmonary disease characterized by airway inflammation,
remodeling, and hyperresponsiveness. Vascular endothelial growth factor (VEGF) and …

Targeting eosinophils in chronic respiratory diseases using nanotechnology-based drug delivery

P Sharma, DS Dhanjal, C Chopra… - Chemico-Biological …, 2022 - Elsevier
Abstract Asthma, COPD, COVID-19, EGPA, Lung cancer, and Pneumonia are major chronic
respiratory diseases (or CRDs) affecting millions worldwide and account for substantial …

Heterogeneity of asthma–chronic obstructive pulmonary disease (COPD) overlap from a cohort of patients with severe asthma and COPD

JY Choi, CK Rhee, KH Yoo, KS Jung… - Therapeutic …, 2023 - journals.sagepub.com
Background: A considerable proportion of patients have features of both asthma and chronic
obstructive pulmonary disease (COPD) simultaneously, called asthma–COPD overlap …

Differential airway remodeling changes were observed in patients with asthma COPD overlap compared to patients with asthma and COPD alone

S Dey, W Lu, HC Weber, S Young… - … of Physiology-Lung …, 2022 - journals.physiology.org
Management of patients with asthma COPD overlap (ACO) is clinically challenging due to
insufficient evidence of pathological changes in these patients. In this cross-sectional study …