Fourth generation biofuel from genetically modified algal biomass: Challenges and future directions

H Shokravi, Z Shokravi, M Heidarrezaei, HC Ong… - Chemosphere, 2021 - Elsevier
Genetic engineering applications in the field of biofuel are rapidly expanding due to their
potential to boost biomass productivity while lowering its cost and enhancing its quality …

What can exome sequencing do for you?

J Majewski, J Schwartzentruber, E Lalonde… - Journal of medical …, 2011 - jmg.bmj.com
Recent advances in next-generation sequencing technologies have brought a paradigm
shift in how medical researchers investigate both rare and common human disorders. The …

Genomic medicine: a decade of successes, challenges, and opportunities

JJ McCarthy, HL McLeod, GS Ginsburg - Science translational …, 2013 - science.org
Genomic medicine—an aspirational term 10 years ago—is gaining momentum across the
entire clinical continuum from risk assessment in healthy individuals to genome-guided …

Disclosure of individual genetic data to research participants: the debate reconsidered

AL Bredenoord, HY Kroes, E Cuppen, M Parker… - Trends in Genetics, 2011 - cell.com
Despite extensive debate, there is no consensus on whether individual genetic data should
be disclosed to research participants. The emergence of whole-genome sequencing …

[HTML][HTML] To tell or not to tell? A systematic review of ethical reflections on incidental findings arising in genetics contexts

GM Christenhusz, K Devriendt, K Dierickx - European Journal of Human …, 2013 - nature.com
Any test that produces visual images or digital or genetic sequences will tend to produce
incidental findings because more will be visible than what was originally sought. We …

Genetics and genetic testing in congenital heart disease

JR Cowan, SM Ware - Clinics in perinatology, 2015 - perinatology.theclinics.com
The impact of congenital heart defects (CHDs) is profound. With a traditionally cited
incidence of 8 per 1000 live births (w1%), and a need for expert cardiologic intervention in 3 …

[HTML][HTML] Ethical issues in human genomics research in developing countries

J De Vries, SJ Bull, O Doumbo, M Ibrahim… - BMC medical …, 2011 - Springer
Background Genome-wide association studies (GWAS) provide a powerful means of
identifying genetic variants that play a role in common diseases. Such studies present …

Feedback of individual genetic results to research participants: in favor of a qualified disclosure policy

AL Bredenoord, NC Onland‐Moret… - Human …, 2011 - Wiley Online Library
This article discusses whether and when researchers have a moral obligation to feedback
individual genetic research results. This unsettled debate has rapidly gained in urgency in …

Ethical issues raised by whole genome sequencing

W Pinxten, HC Howard - Best Practice & Research Clinical …, 2014 - Elsevier
While there is ongoing discussion about the details of implementation of whole genome
sequencing (WGS) and whole exome sequencing (WES), there appears to be a consensus …

'Omics' and endocrine-disrupting chemicals—new paths forward

C Messerlian, RM Martinez, R Hauser… - Nature Reviews …, 2017 - nature.com
The emerging field of omics—large-scale data-rich biological measurements of the genome—
provides new opportunities to advance and strengthen research into endocrine-disrupting …