Fourth generation biofuel from genetically modified algal biomass: Challenges and future directions
Genetic engineering applications in the field of biofuel are rapidly expanding due to their
potential to boost biomass productivity while lowering its cost and enhancing its quality …
potential to boost biomass productivity while lowering its cost and enhancing its quality …
What can exome sequencing do for you?
Recent advances in next-generation sequencing technologies have brought a paradigm
shift in how medical researchers investigate both rare and common human disorders. The …
shift in how medical researchers investigate both rare and common human disorders. The …
Genomic medicine: a decade of successes, challenges, and opportunities
JJ McCarthy, HL McLeod, GS Ginsburg - Science translational …, 2013 - science.org
Genomic medicine—an aspirational term 10 years ago—is gaining momentum across the
entire clinical continuum from risk assessment in healthy individuals to genome-guided …
entire clinical continuum from risk assessment in healthy individuals to genome-guided …
Disclosure of individual genetic data to research participants: the debate reconsidered
Despite extensive debate, there is no consensus on whether individual genetic data should
be disclosed to research participants. The emergence of whole-genome sequencing …
be disclosed to research participants. The emergence of whole-genome sequencing …
[HTML][HTML] To tell or not to tell? A systematic review of ethical reflections on incidental findings arising in genetics contexts
GM Christenhusz, K Devriendt, K Dierickx - European Journal of Human …, 2013 - nature.com
Any test that produces visual images or digital or genetic sequences will tend to produce
incidental findings because more will be visible than what was originally sought. We …
incidental findings because more will be visible than what was originally sought. We …
Genetics and genetic testing in congenital heart disease
JR Cowan, SM Ware - Clinics in perinatology, 2015 - perinatology.theclinics.com
The impact of congenital heart defects (CHDs) is profound. With a traditionally cited
incidence of 8 per 1000 live births (w1%), and a need for expert cardiologic intervention in 3 …
incidence of 8 per 1000 live births (w1%), and a need for expert cardiologic intervention in 3 …
[HTML][HTML] Ethical issues in human genomics research in developing countries
Background Genome-wide association studies (GWAS) provide a powerful means of
identifying genetic variants that play a role in common diseases. Such studies present …
identifying genetic variants that play a role in common diseases. Such studies present …
Feedback of individual genetic results to research participants: in favor of a qualified disclosure policy
AL Bredenoord, NC Onland‐Moret… - Human …, 2011 - Wiley Online Library
This article discusses whether and when researchers have a moral obligation to feedback
individual genetic research results. This unsettled debate has rapidly gained in urgency in …
individual genetic research results. This unsettled debate has rapidly gained in urgency in …
Ethical issues raised by whole genome sequencing
W Pinxten, HC Howard - Best Practice & Research Clinical …, 2014 - Elsevier
While there is ongoing discussion about the details of implementation of whole genome
sequencing (WGS) and whole exome sequencing (WES), there appears to be a consensus …
sequencing (WGS) and whole exome sequencing (WES), there appears to be a consensus …
'Omics' and endocrine-disrupting chemicals—new paths forward
C Messerlian, RM Martinez, R Hauser… - Nature Reviews …, 2017 - nature.com
The emerging field of omics—large-scale data-rich biological measurements of the genome—
provides new opportunities to advance and strengthen research into endocrine-disrupting …
provides new opportunities to advance and strengthen research into endocrine-disrupting …