Optimized whole-genome sequencing workflow for tumor diagnostics in routine pathology practice
KG Samsom, LJW Bosch, LJ Schipper, D Schout… - Nature protocols, 2024 - nature.com
Two decades after the genomics revolution, oncology is rapidly transforming into a genome-
driven discipline, yet routine cancer diagnostics is still mainly microscopy based, except for …
driven discipline, yet routine cancer diagnostics is still mainly microscopy based, except for …
[HTML][HTML] Unraveling Emerging Anal Cancer Clinical Biomarkers from Current Immuno-Oncogenomics Advances
S Iseas, G Mariano, L Gros, N Baba-Hamed… - Molecular Diagnosis & …, 2024 - Springer
Anal squamous cell carcinoma (ASCC) is a rare gastrointestinal malignancy associated with
high-risk human papillomavirus (HPV) and is currently one of the fastest-growing causes of …
high-risk human papillomavirus (HPV) and is currently one of the fastest-growing causes of …
[HTML][HTML] Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders
BM Huffman, H Singh, LR Ali, N Horick… - … for Immunotherapy of …, 2024 - ncbi.nlm.nih.gov
Original research: Biomarkers of pembrolizumab efficacy in advanced anal squamous cell
carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders - PMC Back …
carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders - PMC Back …
[HTML][HTML] Investigation of the potential effects of estrogen receptor modulators on immune checkpoint molecules
N Abramenko, F Vellieux, K Veselá, Z Kejík… - Scientific Reports, 2024 - nature.com
Immune checkpoints regulate the immune system response. Recent studies suggest that
flavonoids, known as phytoestrogens, may inhibit the PD-1/PD-L1 axis. We explored the …
flavonoids, known as phytoestrogens, may inhibit the PD-1/PD-L1 axis. We explored the …
[HTML][HTML] New-generation technologies for spatial tissue analysis, indispensable tools for deciphering intratumor heterogeneity in the development of antibody-drug …
N Radosevic-Robin, M Kossai… - Translational Breast …, 2023 - ncbi.nlm.nih.gov
Technologies allowing in situ tissue molecular analysis of the “high-plex” type (> 20
molecules per tissue section) are the 21 st century inventions that are revolutionizing our …
molecules per tissue section) are the 21 st century inventions that are revolutionizing our …