[HTML][HTML] Animal models of anxiety disorders and stress
Anxiety and stress-related disorders are severe psychiatric conditions that affect
performance in daily tasks and represent a high cost to public health. The initial observation …
performance in daily tasks and represent a high cost to public health. The initial observation …
Neuroendocrine pharmacology of stress
GA Carrasco, LD Van de Kar - European journal of pharmacology, 2003 - Elsevier
Exposure to hostile conditions initiates responses organized to enhance the probability of
survival. These coordinated responses, known as stress responses, are composed of …
survival. These coordinated responses, known as stress responses, are composed of …
Serotonin in affective control
P Dayan, QJM Huys - Annual review of neuroscience, 2009 - annualreviews.org
Serotonin is a neuromodulator that is extensively entangled in fundamental aspects of brain
function and behavior. We present a computational view of its involvement in the control of …
function and behavior. We present a computational view of its involvement in the control of …
Serotonin and brain development
MSK Sodhi, E Sanders-Bush - International review of neurobiology, 2004 - Elsevier
Serotonin (5-hydroxytryptamine, 5-HT), the “happy hormone,” has a phylogenetically ancient
role in neural transmission (Turlejski, 1996). Because the serotonergic system has a …
role in neural transmission (Turlejski, 1996). Because the serotonergic system has a …
Do animal models of anxiety predict anxiolytic-like effects of antidepressants?
F Borsini, J Podhorna, D Marazziti - Psychopharmacology, 2002 - Springer
Chronically administered antidepressant drugs, particularly selective serotonin (5-HT)
reuptake inhibitors (SSRIs), are clinically effective in the treatment of all anxiety disorders …
reuptake inhibitors (SSRIs), are clinically effective in the treatment of all anxiety disorders …
Serotonin in fear conditioning processes
EP Bauer - Behavioural brain research, 2015 - Elsevier
This review describes the latest developments in our understanding of how the serotonergic
system modulates Pavlovian fear conditioning, fear expression and fear extinction. These …
system modulates Pavlovian fear conditioning, fear expression and fear extinction. These …
Glucocorticoid receptor activation is involved in producing abnormal phenotypes of single-prolonged stress rats: a putative post-traumatic stress disorder model
K Kohda, K Harada, K Kato, A Hoshino, J Motohashi… - Neuroscience, 2007 - Elsevier
Post-traumatic stress disorder (PTSD) is a stress-related mental disorder caused by
traumatic experience, and presents with characteristic symptoms, such as intrusive …
traumatic experience, and presents with characteristic symptoms, such as intrusive …
Reward processing by the dorsal raphe nucleus: 5-HT and beyond
The dorsal raphe nucleus (DRN) represents one of the most sensitive reward sites in the
brain. However, the exact relationship between DRN neuronal activity and reward signaling …
brain. However, the exact relationship between DRN neuronal activity and reward signaling …
Acute selective serotonin reuptake inhibitors increase conditioned fear expression: blockade with a 5-HT2C receptor antagonist
NS Burghardt, DEA Bush, BS McEwen, JE LeDoux - Biological psychiatry, 2007 - Elsevier
BACKGROUND: Selective serotonin reuptake inhibitors (SSRIs) effectively treat various
anxiety disorders, although symptoms of anxiety are often exacerbated during early stages …
anxiety disorders, although symptoms of anxiety are often exacerbated during early stages …