Importance A National Institute on Aging and Alzheimer's Association workgroup proposed a
research framework for Alzheimer disease in which biomarker classification of research …

Objective To estimate the annual incidence and prevalence of and frequency of mortality
associated with antiphospholipid syndrome (APS). Methods An inception cohort of patients …

Importance A National Institute on Aging–Alzheimer's Association (NIA-AA) workgroup
recently published a research framework in which Alzheimer disease is defined by …

Objective To determine population-based incidence estimates of basal cell carcinoma
(BCC) and cutaneous squamous cell carcinoma (cSCC). Patients and Methods We …

Background Mitral regurgitation is the most common valve disease worldwide but whether
the community-wide prevalence, poor patient outcomes, and low rates of surgical treatment …

Background: The epidemiology of osteomyelitis in the United States is largely unknown. The
purpose of this study was to determine long-term secular trends in the incidence of …

Aims To define the hitherto unknown aetiology/mechanism distributions of mitral
regurgitation (MR) in the community and the linked clinical characteristics/outcomes …

Background A new classification for biomarkers in Alzheimer's disease and cognitive ageing
research is based on grouping the markers into three categories: amyloid deposition (A) …

Objective: To estimate rates of progression from mild cognitive impairment (MCI) to dementia
and of reversion from MCI to being cognitively normal (CN) in a population-based cohort …

Importance Changes over time in the incidence of parkinsonism and Parkinson disease
(PD) remain uncertain. Objective To investigate secular trends (period effects) and birth …